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Best Prop Bets for Titans and Bills on Monday Night Football

Josh Allen may be in the spotlight for Buffalo but there are several other playmakers to bet on in Week 2.

The 10-point spread for the Titans-Bills "Monday Night Football" game in Buffalo tells us the oddsmakers don’t expect a close contest.

Even though Tennessee won when these teams played in 2021, the Super Bowl favorite Bills are favored by two scores after they dominated the Rams in Week 1. If Buffalo indeed puts this game out of reach, one of the best ways to stay engaged, beyond following your fantasy football players’ performance, is by placing a few player prop bets.

Here are three that I like in this matchup.

Devin Singletary Anytime Touchdown Scorer (+115)

Singletary had 10 touches against the Rams and looked good each time he had the ball. He was efficient, totaling 62 yards on 10 touches, but did not find the end zone. Singletary was on a touchdown tear near the end of the 2021 season—he scored six times in the final four games of the season and three more times across two playoff games. He already beat out Zack Moss and rookie James Cook for the most carries among Bills running backs in Week 1, but it was Allen who ran in the team's lone rushing score and also led the way with 10 carries. So long as Singletary gets the requisite carries, he should break through with a red-zone score in a game script that should see to it that the Bills run the ball often in the second half.

Ryan Tannehill Under 209.5 Yards (-114)

Tannehill finished with less than 200 passing yards in seven games last season. Granted, he finished well above this mark a week ago against New York (266) but that was against a lesser defense than what he’s about to go up against. Add in the fact that he’ll be missing one of, if not both of his top receivers from last week (wide receiver Kyle Philips is questionable and running back Dontrell Hilliard is out), and the task of getting above 200 gets even tougher. The Bills held Matthew Stafford to 240 yards last week and that was on 41 attempts with much better weapons at his disposal.

Stefon Diggs Over 76.5 Receiving Yards (-114)

The over for the top receiver in one of the league’s top passing offenses feels safe and what’s even better is that this number feels a bit low. Diggs caught eight of nine targets for 122 yards last week, all of which led the team. There’s also a chance Gabe Davis (ankle) misses this game, which might lead Allen to funnel even more of his high-value targets Diggs’ way. He broke free for a 53-yard reception last week. This feels like a bet that could hit by halftime.