While none of the 112 No. 16 seeds has won a game in the NCAA Tournament (more on that below), six No. 15 seeds have shocked No. 2s since the field expanded to 64 teams in 1985. And two of them took place during this year's March Madness. Here's our look at the biggest upsets and closest calls from college basketball's NCAA Tournament.
THE BIGGEST UPSETS: No. 2 vs. No. 15 (7-109)