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10 College Football Picks Against the Spread for Week 10

Justin Jackson

Justin Jackson

The Week 10 edition of college football’s picks against the spread features predictions for some of Saturday’s biggest games, including Nebraska-Ohio State, Arkansas-LSU, Alabama-LSU and Northwestern-Wisconsin. Additionally, conference matchups such as Kentucky-Georgia, SMU-Memphis, Texas Tech-Texas, and Penn State-Iowa feature lines or odds that caught our attention for Week 10. Here are 10 predictions or picks against the spread for this weekend's action:

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10 CFB Picks Against the Spread for Week 10

North Carolina (-10.5) over Georgia Tech

The North Carolina offense has performed at a very high level in games not played in a dome (opener vs. Georgia) and not played in a hurricane (vs. Virginia Tech).

Arkansas (+5.5) over Florida

There’s no doubt the Gators feature one of the nation’s top defenses, but the offense is another issue. In its last two road trips, the Florida offense managed 236 yards (at Vanderbilt) and 231 yards (vs. Georgia in Jacksonville).

SMU (+3) over Memphis

Tom Herman is all the rage for his work at Houston, but Chad Morris — another second-year coach at an AAC school in Texas — deserves a ton of credit for his rebuild at SMU. It’s a bit surprising that the Mustangs, coming off wins over Houston and Tulane (on the road), are a home dog.

Alabama (-7.5) over LSU

LSU is playing inspired football under interim coach Ed Orgeron, but the Tigers will need more than inspiration to beat Alabama. I’m not sure Nick Saban’s team has a weakness.

Northwestern (+7) over Wisconsin

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The Northwestern spread (+27 at Ohio State) looked a bit high last week. It was. The same goes for this week. The Wildcats are playing good football — even if the betting public hasn’t quite noticed.

Nebraska (+17) over Ohio State

Ohio State has been a bit sluggish of late, having failed to score more than 24 points in regulation in each of the last three games. Nebraska will have a tough time winning in Columbus — but should be able keep things close.

Georgia (-2.5) over Kentucky

Kentucky has surprised with a 4–2 record in the SEC, but keep in mind that those wins have come against South Carolina and Vanderbilt at home by seven points apiece, by two points at home vs. Mississippi State and at Missouri. Not exactly murder’s row.

Penn State (-7.5) over Iowa

Penn State was ranked No. 12 in the initial College Football Playoff rankings. That seems a bit high. This is a good team — just not sure it’s one of the top 15 teams in the nation.

Texas Tech (+3.5) over Texas

Texas has been unable to handle prosperity in the Charlie Strong era. The Longhorns picked up a huge win last week vs. Baylor. I smell letdown.   

Texas A&M (-13.5) over Mississippi State

Texas A&M was No. 4 in the initial CFB Playoff poll, but the Aggies’ spot is far from secure. They need to keep winning — and look good doing so.

Last week: 6-4

Season: 29-30-1