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10 College Football Picks Against the Spread for Week 7

Mitch Trubisky

Mitch Trubisky

The Week 7 edition of college football’s picks against the spread features predictions for some of Saturday’s biggest games, including Alabama-Tennessee, Ohio State-Wisconsin and Notre Dame-Stanford. Additionally, conference matchups such as Clemson-NC State, USC-Arizona, Oklahoma-Kansas State and Northwestern-Michigan State feature lines or odds that caught our attention for Week 7. Here are 10 predictions or picks against the spread for this weekend's action:

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10 CFB Picks Against the Spread for Week 7

NC State (+17.5) over Clemson

The Wolfpack have gained over 500 yards in three of their five games (and three of their four not played in a Hurricane). This team has enough offensive weapons to make Clemson sweat … for a while.

Related: Predictions for Every College Football Game in Week 7

Kansas State (+10.5) over Oklahoma

Kansas State leads the Big 12 in total defense (310.2 ypg) and ranks last in the league in total offense (344.2 ypg). Oklahoma’s two wins over Power 5 opponents have come by six points and five points. K-State keeps it close.

Northwestern (+4.5) over Michigan State

Northwestern has played better of late after a disastrous 0–2 start, most notably in last week’s 38–31 win at Iowa. There’s been nothing fluky about Michigan State’s recent three-game slide; the Spartans have not played well since their Week 2 win at Notre Dame.

North Carolina (+7.5) at Miami

This line seems to be a bit high considering that North Carolina has not lost an ACC regular-season game not played in a Hurricane since the end of the 2014 season.

Alabama (-13) over Tennessee

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Alabama is coming off an incredibly efficient offensive performance against Arkansas; the Crimson Tide averaged 10.1 yards per play, and quarterback Jalen Hurts averaged 14.9 yards on his 17 passing attempts.

Missouri (+13.5) over Florida

Even with Luke Del Rio back at quarterback, the Gators still have issues on offense. The guess here is that Missouri won’t get manhandled like it did two weeks ago at LSU.

Ole Miss (-7.5) at Arkansas

Here’s a scary thought for SEC defenses: Ole Miss has found a running game. The Rebels rushed for 180 vs. Georgia and 263 vs. Memphis.

Notre Dame (-3) over Stanford

Both teams are struggling. Notre Dame has some playmakers on offense. Notre Dame is at home. Take Notre Dame.

Ohio State (-10) at Wisconsin

The schedule hasn’t been overly taxing, but Ohio State is the only team in the nation in the top five in total offense and total defense. Wisconsin doesn’t have the firepower on offense to keep this in single digits.

USC (-8) at Arizona

It’s always dangerous to jump on the USC bandwagon, but the Trojans have seemingly turned a corner in recent weeks.

Last week: 5-4-1

Season: 13-16-1