This Saturday night in central Pennsylvania, two of college football's biggest programs will meet for the first time in a month other than January. Despite having four national championships and four Heisman Trophy winners between them, Auburn and Penn State have never met during the regular season. Their only matchups have been the 1996 Outback Bowl and the 2003 Capital One Bowl. (Penn State won the first, Auburn the second for those who were curious.)
This is not unique. Even with time, television, and conference realignment, there are still some blockbuster matchups we've yet to see in the regular season. Here are five.
1. Alabama vs. Boise State
From kickoff games to ambitious regular-season matchups, the Crimson Tide seem to have played every major program at least once. The only one that appears to be left is Boise State. That being said, the end result of a meeting between these two schools would likely be a good, old-fashion Alabama ass-whoopin'.
2. Tennessee vs. Texas
Because of several factors ranging from David Crockett to Sam Houston to country music to Cormac McCarthy, no two non-bordering states are linked the way Tennessee and Texas are. Yet the only meetings between these two UT schools were three Cotton Bowl matchups in the '50s and '60s. That will change when the Longhorns join the SEC, but it is amazing that a home-and-home series never happened sooner.
3. Auburn vs. Notre Dame
Had Auburn had not been on probation in 1993, there is always the possibility that its undefeated season could have culminated in a Sugar Bowl matchup with Notre Dame. That's about the closest these two teams have ever come to playing each other even though they have 13 national championships and 10 Heisman winners between them.
4. Clemson vs. Ohio State
Since the Buckeyes and Tigers have played in the postseason four times over the past eight years, this contest might not be the first to come to mind. However, the two schools have never played each other during the regular season. Their first meeting came in the 1978 Gator Bowl when Ohio State's Woody Hayes punched Clemson nose guard Charlie Bauman and was fired.
5. Oklahoma vs. Michigan
Michigan is college football's all-time winningest program and Oklahoma is No. 6. You would think these two schools would have met at some point during the regular season, right? In actuality, their only meeting was in the 1976 Orange Bowl, where the Sooners beat the Wolverines 14-6 to secure their second consecutive national title.
— Written by Aaron Tallent, who is part of the Athlon Contributor Network. Tallent is a writer whose articles have appeared in The Sweet Science, FOX Sports' Outkick the Coverage, Liberty Island and The Washington Post. Follow him on Twitter at @AaronTallent.