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College Fantasy Football: Week 12 DFS Picks Saturday (Nov. 19) Games

Michael Penix Jr., Washington Huskies

Week 12 of the 2022 college football starts on Saturday, Nov. 19. That means it’s time to pick your optimal DraftKings college football fantasy lineup. Fortunately, our college football fantasy experts are ready to help. Players from 14 matchups are available to be selected on DraftKings for the first slate on Saturday, including TCU-Baylor, Indiana-Michigan State, Illinois-Michigan and Washington State-Arizona. The afternoon slate features six games to select players, including NC State-Louisville, Georgia-Kentucky, Texas-Kansas and Ohio State-Maryland. The first night contest features eight contests to make selections from, including Ole Miss-Arkansas, USC-UCLA, Oklahoma State-Oklahoma, and Tennessee-South Carolina. The final slate includes four games, as players can be selected from UNLV-Hawaii, Utah-Oregon, Fresno State-Nevada, and San Jose State-Utah State.

The first few weeks of the season are always difficult to predict, but we have a better idea by early November of rosters, breakdown of personnel and targets or carries per team. Here’s what our best Week 12 (Nov. 19) college fantasy football DFS lineup looks like for Saturday's matchups:

College Fantasy Football DFS Picks

Saturday DFS Slate (Noon ET - 14 games) - Lineup 1

QB: Clayton Tune, Houston (at East Carolina - $8,100)

RB: Braelon Allen, Wisconsin (at Nebraska - $7,000)

RB: Nick Singleton, Penn State (at Rutgers - $5,800)

WR: Jayden Reed, Michigan State (vs. Indiana - $5,600)

WR: Quentin Johnston, TCU (at Baylor - $7,100)

WR: C.J. Johnson, East Carolina (vs. Houston - $6,200)

Flex: Nakia Watson, Washington State (at Arizona - $3,800)

S-Flex: Holton Ahlers, East Carolina (vs. Houston - $6,200)

Saturday DFS Slate (Noon ET - 14 games) - Lineup 2

QB: Holton Ahlers, East Carolina (vs. Houston - $6,200)

RB: Bijan Robinson, Texas (at Kansas - $9,100)

RB: Kendre Miller, TCU (at Baylor - $6,800)

WR: Jayden Reed, Michigan State (vs. Indiana - $5,600)

WR: Matthew Golden, Houston (at East Carolina - $5,300)

WR: Xavier Worthy, Texas (at Kansas - $6,500)

Flex: Dallan Hayden, Ohio State (at Maryland - $3,700)
*Be sure to check pregame injury report on Ohio State's RBs

S-Flex: Cameron Ward, Washington State (at Arizona - $6,800)


Saturday DFS Slate (Noon ET - 14 games) - Lineup 3

QB: C.J. Stroud, Ohio State (at Maryland - $9,600)

RB: Braelon Allen, Wisconsin (at Nebraska - $7,000)

RB: Audric Estime, Notre Dame (vs. Boston College - $5,700)

WR: Emeka Egbuka, Ohio State (at Maryland - $7,700)

WR: Samuel Brown, Houston (at East Carolina - $4,200)

WR: Jayden Reed, Michigan State (vs. Indiana - $5,600)

Flex: Nakia Watson, Washington State (at Arizona - $3,800)

S-Flex: Holton Ahlers, East Carolina (vs. Houston - $6,200)


Saturday DFS Slate (Noon ET - 14 games) - Lineup 4

QB: Clayton Tune, Houston (at East Carolina - $8,100)

RB: Bijan Robinson, Texas (at Kansas - $9,100)

RB: Nakia Watson, Washington State (at Arizona - $3,800)

WR: Emeka Egbuka, Ohio State (at Maryland - $7,700)

WR: Nathaniel Dell, Houston (at East Carolina - $8,200)

WR: Ja'Tavion Sanders, Texas (at Kansas - $4,500)

Flex: Logan Diggs, Notre Dame (vs. Boston College - $4,600)

S-Flex: Dallan Hayden, Ohio State (at Maryland - $3,700)*
*Be sure to check pregame injury report on Ohio State's RBs


Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 1

QB: C.J. Stroud, Ohio State (at Maryland - $9,600)

RB: Bijan Robinson, Texas (at Kansas - $9,100)

RB: Will Shipley, Clemson (vs. Miami - $6,500)

WR: Ja'Tavion Sanders, Texas (at Kansas - $4,500)

WR: Julian Fleming, Ohio State (at Maryland - $5,000)

WR: Kearis Jackson, Georgia (at Kentucky - $4,000)

Flex: Nick Singleton, Penn State (at Rutgers - $5,800)

S-Flex: Lawrence Arnold, Kansas (vs. Texas - $5,400)


Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 2

QB C.J. Stroud, Ohio State (at Maryland - $9,600)

RB: Bijan Robinson, Texas (at Kansas - $9,100)

RB: Kaytron Allen, Penn State (at Rutgers - $5,600)

WR: Marvin Harrison Jr., Ohio State (at Maryland - $8,100)

WR: Ja'Tavion Sanders, Texas (at Kansas - $4,500)

WR: Theo Johnson, Penn State (at Rutgers - $3,600)

Flex: Dallan Hayden, Ohio State (at Maryland - $3,700)
**Be sure to check pregame injury report on Ohio State's RBs

S-Flex: Nick Singleton, Penn State (at Rutgers - $5,800)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 1

QB: Caleb Williams, USC (at UCLA - $9,000)

RB: Zach Charbonnet, UCLA (vs. USC - $8,000)

RB: Josh Williams, LSU (vs. UAB - $5,100)

WR: Bryson Green, Oklahoma State (vs. Oklahoma - $5,800)

WR: Mario Williams, USC (at UCLA - $5,900)

WR: Ramel Keyton, Tennessee (at South Carolina - $4,900)

Flex: Taylor Morin, Wake Forest (vs. Syracuse - $5,400)

S-Flex: Hunter Dekkers, Iowa State (vs. Texas Tech - $5,400)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 2

QB: Michael Penix Jr., Washington (vs. Colorado - $7,900)

RB: Quinshon Judkins, Ole Miss (at Arkansas - $7,000)

RB: Sean Tucker, Syracuse (at Wake Forest - $6,200)

WR: Jalen McMillan, Washington (vs. Colorado - $6,600)

WR: Tahj Washington, USC (at UCLA – $5,700)

WR: Jonathan Mingo, Ole Miss (at Arkansas - $5,200)

Flex: Matt Landers, Arkansas (vs. Ole Miss - $5,200)

S-Flex: Raleek Brown, USC (at UCLA - $5,000)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 3

QB: Caleb Williams, USC (at UCLA - $9,000)

RB: Zach Charbonnet, UCLA (vs. USC - $8,000)

RB: Josh Williams, LSU (vs. UAB - $5,100)

WR: Jaheim Bell, South Carolina (vs. Tennessee - $3,900)

WR: Oronde Gadsden II, Syracuse (at Wake Forest – $5,900)

WR: Jordan Addison, USC (at UCLA – $7,700)

Flex: Matt Landers, Arkansas (vs. Ole Miss - $5,200)

S-Flex: Garrett Shrader, Syracuse (at Wake Forest - $5,100)


Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 4

QB: Hendon Hooker, Tennessee (at South Carolina - $8,200)

RB: Zach Charbonnet, UCLA (vs. USC - $8,000)

RB: Justice Ellison, Wake Forest (vs. Syracuse - $5,400)

WR: Ramel Keyton, Tennessee (at South Carolina - $4,900)

WR: Taylor Morin, Wake Forest (vs. Syracuse - $5,400)

WR: Kayshon Boutte, LSU (vs. UAB - $5,600)

Flex: Cartevious Norton, Iowa State (vs. Texas Tech - $4,600)

S-Flex: Michael Penix Jr., Washington (vs. Colorado - $7,900)


Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 5

QB: Hendon Hooker, Tennessee (at South Carolina - $8,200)

RB: Zach Charbonnet, UCLA (vs. USC - $8,000)

RB: Austin Jones, USC (at UCLA - $5,400)

WR: Tahj Washington, USC (at UCLA - $5,700)

WR: Jaheim Bell, South Carolina (vs. Tennessee - $3,900)

WR: Matt Landers, Arkansas (vs. Ole Miss - $5,200)

Flex: Sean Tucker, Syracuse (at Wake Forest - $6,200)

S-Flex: Quinshon Judkins, Ole Miss (at Arkansas - $7,000)


Saturday DFS Slate (9:45 p.m. ET - 4 games) - Lineup 1

QB: Jake Haener, Fresno State (at Nevada - $7,500)

RB: Aidan Robbins, UNLV (at Hawaii - $6,400)

RB: Jordan Mims, Fresno State (at Nevada - $6,700)

WR: Jalen Moreno-Cropper, Fresno State (at Nevada - $7,200)

WR: Dalton Kincaid, Utah (at Oregon - $6,200)

WR: Kris Hutson, Oregon (vs. Utah - $5,100)

Flex: Kairee Robinson, San Jose State (at Utah State - $5,400)

S-Flex: Doug Brumfield, UNLV (at Hawaii - $5,400)

Saturday DFS Slate (9:45 p.m. ET - 4 games) - Lineup 2

QB: Cameron Rising, Utah (at Oregon - $8,900)

RB: Aidan Robbins, UNLV (at Hawaii - $6,400)

RB: Kairee Robinson, San Jose State (at Utah State - $5,400)

WR: Jonah Panoke, Hawaii (vs. UNLV - $4,200)

WR: Kyle Williams, UNLV (at Hawaii - $5,300)

WR: Devaughn Vele, Utah (at Oregon - $5,500)

Flex: Dedrick Parson, Hawaii (vs. UNLV ($5,500)

S-Flex: Jake Haener, Fresno State (at Nevada - $7,500)

Podcast: Week 12 Preview, Predictions and Picks Against the Spread + Reaction to CFB Playoff Top 25 Rankings