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College Fantasy Football: Week 4 DFS Picks Saturday (Sept. 24) Games

Michael Penix Jr., Washington Huskies

Week 4 of the 2022 college football starts on Saturday, Sept. 24. That means it’s time to pick your optimal DraftKings college football fantasy lineup. Fortunately, our college football fantasy experts are ready to help. Players from 13 matchups are available to be selected on DraftKings for the first slate on Saturday, including Maryland-Michigan, Clemson-Wake Forest and Baylor-Iowa State. The afternoon slate features six games to select players, including Florida-Tennessee, Oregon-Washington State and Notre Dame-North Carolina. The first night contest features eight contests to make selections from, including Arkansas-Texas A&M, Boston College-Florida State and USC-Oregon State. The final slate includes four games, as players can be selected from Wyoming-BYU, Stanford-Washington, Arizona State-Utah and Western Michigan-San Jose State.

The first few weeks of the season are always difficult to predict. Here’s what our best Week 4 (Sept. 24) college fantasy football DFS lineup looks like for Saturday's matchups:

College Fantasy Football DFS Picks

Saturday DFS Slate (Noon ET - 13 games) - Lineup 1

QB: Hendon Hooker, Tennessee (vs. Florida - $8,100)

RB: Bijan Robinson, Texas (at Texas Tech - $8,300)

RB: Blake Corum, Michigan (vs. Maryland - $7,900)

WR: Donovan Ollie, Washington State (vs. Oregon - $3,500)

WR: Dominic Lovett, Missouri (at Auburn - $5,000)

WR: Roman Wilson, Michigan (vs. Maryland - $3,900)

Flex: Xavier Hutchinson, Iowa State (vs. Baylor - $6,700)

S-Flex: Riley Leonard, Duke (at Kansas - $6,000)

Saturday DFS Slate (Noon ET - 13 games) - Lineup 2

QB: Tanner Mordecai, SMU (vs. TCU - $7,800)

RB: Tank Bigsby, Auburn (vs. Missouri - $6,000)

RB: Will Shipley, Clemson (at Wake Forest - $6,700)

WR: Rashee Rice, SMU (vs. TCU - $8,600)

WR: Donovan Ollie, Washington State (vs. Oregon - $3,500)

WR: Terrance Ferguson, Oregon (at Washington State - $4,000)

Flex: Myles Price, Texas Tech (vs. Texas - $5,400)

S-Flex: Jalon Daniels, Kansas (vs. Duke - $7,900)

Saturday DFS Slate (Noon ET - 13 games) - Lineup 3

QB: Max Duggan, TCU (at SMU - $7,100)

RB: Audric Estime, Notre Dame (at North Carolina - $5,100)

RB: Will Shipley, Clemson (at Wake Forest - $6,700)

WR: Rashee Rice, SMU (vs. TCU - $8,600)

WR: Beaux Collins, Clemson (at Wake Forest - $5,800)

WR: Dominic Lovett, Missouri (at Auburn - $5,000)

Flex: Xavier Worthy, Texas (at Texas Tech - $6,300)

S-Flex: Cameron Ward, Washington State (vs. Oregon - $5,000)

Saturday DFS Slate (Noon ET - 13 games) - Lineup 4

QB: J.J. McCarthy, Michigan (vs. Maryland – $7,700)

RB: Bijan Robinson, Texas (at Texas Tech - $8,300)

RB: Tank Bigsby, Auburn (vs. Missouri - $6,000)

WR: Roman Wilson, Michigan (vs. Maryland - $3,900)

WR: Troy Franklin, Oregon (at Washington State - $5,200)

WR: Quentin Johnston, TCU (at SMU - $7,600)

Flex: Dominic Lovett, Missouri (at Auburn - $5,000)

S-Flex: DJ Uiagalelei, Clemson (at Wake Forest – $6,300)

Saturday DFS Slate (3:30 p.m. ET - 6 games) - Lineup 1

QB: Hendon Hooker, Tennessee (vs. Florida - $8,100)

RB: Bijan Robinson, Texas (at Texas Tech - $8,300)

RB: Audric Estime, Notre Dame (at North Carolina - $5,100)

WR: Xavier Worthy, Texas (at Texas Tech - $6,300)

WR: Donovan Ollie, Washington State ($3,500)

WR: Bru McCoy, Tennessee (vs. Florida - $5,000)

Flex: Myles Price, Texas Tech (vs. Texas - $5,400)

S-Flex: Ben Bryant, Cincinnati (vs. Indiana - $7,200)

Saturday DFS Slate (3:30 p.m. ET - 6 games) - Lineup 2

QB: Hendon Hooker, Tennessee (vs. Florida - $8,100)

RB Bijan Robinson, Texas (at Texas Tech - $8,300)

RB: Trevor Etienne, Florida (at Tennessee - $3,200)

WR: Cam Camper, Indiana (at Cincinnati - $5,600)

WR: Xavier Worthy, Texas (at Texas Tech - $6,300)

WR: Jalin Hyatt, Tennessee (vs. Florida - $6,800)

Flex: Jayden Reed, Michigan State (vs. Minnesota - $6,600)*
Be sure to monitor pregame news for an update on his injury status

S-Flex: Cameron Ward, Washington State (vs. Oregon - $5,000)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 1

QB: Will Levis, Kentucky (vs. Northern Illinois - $8,300)

RB: Trey Benson, Florida State (vs. Boston College -$5,100)

RB: Deshaun Fenwick, Oregon State (vs. USC - $5,500)

WR: Marvin Harrison Jr., Ohio State (vs. Wisconsin - $7,000)

WR: Dane Key, Kentucky (vs. Northern Illinois - $6,300)

WR: Ainias Smith, Texas A&M (vs. Arkansas - $5,900)

Flex: Deuce Vaughn, Kansas State (at Oklahoma - $6,700)

S-Flex: Aidan Robbins, UNLV (at Utah State - $4,700)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 2

QB: Caleb Williams, USC (at Oregon State - $10,200)

RB: Aidan Robbins, UNLV (at Utah State - $4,700)

RB: Deuce Vaughn, Kansas State (at Oklahoma - $6,700)

WR: Johnny Wilson, Florida State (vs. Boston College - $5,500)

WR: Tre’Shaun Harrison, Oregon State ($5,300)

WR: Brian Cobbs, Utah State (vs. UNLV - $4,300)

Flex: Deshaun Fenwick, Oregon State (vs. USC - $5,500)

S-Flex: K.J. Jefferson, Arkansas (vs. Texas A&M - $7,000)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 3

QB: Caleb Williams, USC (at Oregon State - $10,200)

RB: Deshaun Fenwick, Oregon State (vs. USC - $5,500)

RB: Aidan Robbins, UNLV (at Utah State - $4,700)

WR: Jordan Addison, USC (at Oregon State - $10,300)

WR: Brian Cobbs, Utah State (vs. UNLV - $4,300)

WR: Chimere Dike, Wisconsin (at Ohio State - $4,600)

Flex: Evan Stewart, Texas A&M (vs. Arkansas - $3,600)

S-Flex: Deuce Vaughn, Kansas State (at Oklahoma - $6,700)

Saturday DFS Slate (7 p.m. ET - 8 games) - Lineup 4

QB: Caleb Williams, USC (at Oregon State - $10,200)

RB: Deuce Vaughn, Kansas State (at Oklahoma - $6,700)

RB: Devon Achane, Texas A&M (vs. Arkansas - $6,300)

WR: Mario Williams, USC (at Oregon State - $6,800)

WR: Zay Flowers, Boston College (at Florida State - $5,800)

WR: Evan Stewart, Texas A&M (vs. Arkansas - $3,600)

Flex: Deshaun Fenwick, Oregon State (vs. USC - $5,500)

S-Flex: Max Johnson, Texas A&M (vs. Arkansas - $4,700)

Saturday DFS Slate (10:15 p.m. ET - 4 games) - Lineup 1

QB: Michael Penix Jr., Washington (vs. Stanford - $8,400)

RB: Tavion Thomas, Utah (at Arizona State - $8,600)

RB: Sean Tyler, Western Michigan (at San Jose State - $5,700)

WR: Michael Wilson, Stanford (at Washington - $5,200)

WR: Elijah Cooks, San Jose State (vs. Western Michigan - $4,200)

WR: Brant Kuithe, Utah (at Arizona State - $4,800)

Flex: Jalen McMillan, Washington (vs. Stanford - $7,100)

S-Flex: Chevan Cordeiro, San Jose State (vs. Western Michigan - $5,900)

Saturday DFS Slate (10:15 p.m. ET - 4 games) - Lineup 2

QB: Michael Penix Jr., Washington (vs. Stanford - $8,400)

RB: Tavion Thomas, Utah (at Arizona State - $8,600)

RB: Casey Filkins, Stanford (at Washington - $4,100)

WR: Chase Roberts, BYU (vs. Wyoming - $4,000)

WR: Jalen McMillan, Washington (vs. Stanford - $7,100)

WR: Benjamin Yurosek, Stanford (at Washington - $4,200)

Flex: Titus Swen, Wyoming (at BYU - $5,800)

S-Flex: Jaren Hall, BYU (vs. Wyoming - $7,600)

Podcast: Week 4 Preview, Predictions and Picks Against the Spread