Skip to main content

College Fantasy Football: Week 6 DFS Picks Saturday (Oct. 8) Games

Caleb Williams, USC Trojans Football

Week 6 of the 2022 college football starts on Saturday, Oct. 8. That means it’s time to pick your optimal DraftKings college football fantasy lineup. Fortunately, our college football fantasy experts are ready to help. Players from 14 matchups are available to be selected on DraftKings for the first slate on Saturday, including Missouri-Florida, Tennessee-LSU, Arkansas-Mississippi State, and TCU-Kansas. The afternoon slate features seven games to select players, including Wisconsin-Northwestern, Ole Miss-Vanderbilt, Ohio State-Michigan State, and Washington-Arizona State. The first night contest features nine contests to make selections from, including Oregon-Arizona, Washington State-USC and Florida State-NC State. The final slate includes three games, as players can be selected from Oregon State-Stanford, Hawaii-San Diego State and Fresno State-Boise State.

The first few weeks of the season are always difficult to predict. Here’s what our best Week 6 (Oct. 8) college fantasy football DFS lineup looks like for Saturday's matchups:

College Fantasy Football DFS Picks

Saturday DFS Slate (Noon ET - 13 games) - Lineup 1

QB: Hendon Hooker, Tennessee (at LSU - $8,100)

RB: Quinshon Judkins, Ole Miss (at Vanderbilt - $6,400)

RB: Rocket Sanders, Arkansas (at Miss. State - $6,200)

WR: Bru McCoy, Tennessee (at LSU - $5,700)

WR: Malik Nabers, LSU (vs. Tennessee - $5,300)

WR: Charlie Jones, Purdue (at Maryland - $7,000)

Flex:Ja'Tavion Sanders, Texas (vs. Oklahoma - $3,500)

S-Flex: Will Rogers, Miss. State (vs. Arkansas - $7,700)

Saturday DFS Slate (Noon ET - 13 games) - Lineup 2

QB: Will Rogers, Miss. State (vs. Arkansas - $7,700)

RB: Kendre Miller, TCU (at Kansas - $6,000)

RB: Bijan Robinson, Texas (vs. Oklahoma - $9,000)

WR: Julian Fleming, Ohio State (at Michigan State - $5,000)

WR: Caleb Ducking, Miss. State (vs. Arkansas - $5,500)

WR: Xavier White, Texas Tech (at Oklahoma State - $3,400)

Flex: Xavier Worthy, Texas (vs. Oklahoma - $6,300)

S-Flex: Jalon Daniels, Kansas (vs. TCU - $6,900)

Saturday DFS Slate (Noon ET - 13 games) - Lineup 3

QB: Quinn Ewers, Texas (vs. Oklahoma - $6,500)

RB: Blake Corum, Michigan (at Indiana - $7,900)

RB: Quishon Judkins, Ole Miss (at Vanderbilt - $6,400)

WR: Bru McCoy, Tennessee (at LSU - $5,700)

WR: Dalton Kincaid, Utah (at UCLA - $4,400)

WR: Brennan Presley, Oklahoma State (vs. Texas Tech - $5,100)

Flex: Charlie Jones, Purdue (at Maryland - $7,000)

S-Flex: Jalon Daniels, Kansas (vs. TCU - $6,900)

Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 1

QB: Spencer Sanders, Oklahoma State (vs. Texas Tech - $8,000)

RB: Zach Charbonnet, UCLA (vs. Utah - $6,800)

RB: Quinshon Judkins, Ole Miss (at Vanderbilt - $6,400)

WR: Jayden Reed, Michigan State (vs. Ohio State - $4,900)

WR: Emeka Egbuka, Ohio State (at Michigan State - $6,700)

WR: Dalton Kincaid, Utah (at UCLA - $4,400)

Flex: Xavier White, Texas Tech (at Oklahoma State - $3,400)

S-Flex: Michael Penix Jr., Washington (at Arizona State - $8,500)

Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 2

QB: Spencer Sanders, Oklahoma State (vs. Texas Tech - $8,000)

RB: Kendall Milton, Georgia (vs. Auburn - $5,900)

RB: Miyan Williams, Ohio State (at Michigan State - $7,300)*
*Keep an eye on TreVeyon Henderson’s status. If Henderson plays, pivot to another selection here.

WR: Jalen McMillan, Washington (at Arizona State - $6,200)

WR: Xavier White, Texas Tech (at Oklahoma State - $3,400)

WR: Emeka Egbuka, Ohio State (at Michigan State - $6,700)

Flex: Quinshon Judkins, Ole Miss (at Vanderbilt - $6,400)

S-Flex: Will Sheppard, Vanderbilt (vs. Ole Miss - $5,600)


Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 3

QB: Michael Penix Jr., Washington (at Arizona State - $8,500)

RB: Evan Hull, Northwestern (vs. Wisconsin - $6,300)

RB: Kendall Milton, Georgia (vs. Auburn - $5,900)

WR: Dalton Kincaid, Utah (at UCLA - $4,400)

WR: Brennan Presley, Oklahoma State (vs. Texas Tech - $5,100)

WR: Julian Fleming, Ohio State (at Michigan State - $5,000)

Flex: Zach Charbonnet, UCLA (vs. Utah - $6,800)

S-Flex: Donovan Smith, Texas Tech (at Oklahoma State - $7,000)


Saturday DFS Slate (3:30 p.m. ET - 7 games) - Lineup 4

QB: C.J. Stroud, Ohio State (at Michigan State - $9,200)

RB: Zach Charbonnet, UCLA (vs. Utah - $6,800)

RB: Quinshon Judkins, Ole Miss (at Vanderbilt - $6,400)

WR: Julian Fleming, Ohio State (at Michigan State - $5,000)

WR: Dalton Kincaid, Utah (at UCLA - $4,400)

WR: Jalen McMillan, Washington (at Arizona State - $6,200)

Flex: Brennan Presley, Oklahoma State (vs. Texas Tech - $5,100)

S-Flex: Xazavian Valladay, Arizona State (vs. Washington - $6,700)

Saturday DFS Slate (7:30 p.m. ET - 9 games) - Lineup 1

QB: Caleb Williams, USC (vs. Washington State -$10,200)

RB: Audric Estime, Notre Dame (vs. BYU - $5,500)

RB: Demie Sumo-Karngbaye, NC State (vs. Florida State - $5,000)