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5 College Football Picks Against the Spread (ATS) for Week 4

5 College Football Picks Against the Spread (ATS) for Week 4

5 College Football Picks Against the Spread (ATS) for Week 4

Welcome to the 2020 college football season, SEC. The third power conference to get in the mix takes the field this weekend with defending national champion LSU getting a home game against Mike Leach, and Alabama is on the road to get warmed up for what could be a big season.

Elsewhere in the Week 4 schedule, we see a rare top 256 clash between two former Conference USA foes. Things are starting to heat up with the college football season, but are we getting any better at reading the lines? That's the big question going into Week 4 after a few ups and downs over the last three weeks. And with some pretty big spreads to soak in this week, there could be some good risks floating out there. But in the end, the best teams probably give you the most reasons to feel confident in the picks. Let's ride with some big favorites and a few underdogs this week.

Oklahoma (-28.5) vs. Kansas State

You didn’t need the first two weeks of the season to know that Oklahoma is the cream of the crop in the Big 12. Spencer Rattler and the Sooners offense is already explosive as they'll come in the conference. The Sooners roll at home. Oklahoma 48, Kansas State 13.

College Football Top 25 Rankings: Oklahoma

LSU (-16) vs. Mississippi State

LSU will certainly have some new faces stepping into big shoes his season after winning it all, but Ed Orgeron's Tigers are still going to be incredibly difficult to beat at home. This could be a rude welcome to the SEC for new Mississippi State head coach Mike Leach, as the reigning national champs. Myles Brennan won't be Joe Burrow, but he won't need to be to put up big numbers in his first start in Baton Rouge. LSU 38, Mississippi State 17

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Army (+14) at Cincinnati

The two former Conference USA foes will meet for the first time since 2004, and this will mark the first time either team is ranked in the top 25 for the game (they are actually both ranked for an even more rare event in this series). Army should be able to manage to work enough clock to keep this game from getting out of hand, making a two-touchdown spread something they should be able to cover, but Cincinnati gets the notable win at the end. Cincinnati 34, Army 23

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South Carolina (+3.5) vs. Tennessee

Tennessee has had a rocky start to the season for a few years now, and this one should be no different. Will Muschamp may not have a roster ready to make too much noise in the SEC, but the Vols should be in for a good scrap with the Gamecocks. If Jarrett Guarantano can avoid making some mistakes and keep the offense moving, Tennessee should get out of Columbia with a win. But South Carolina won't allow for the Vols to feel too comfortable in this sloppy opener. Tennessee 24, South Carolina 23

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Alabama (-27.5) at Missouri

Welcome to the SEC, Eli Drinkwitz. The new Missouri head coach gets the unlucky draw of having to face Nick Saban and Alabama in the first game of the season. The Crimson Tide should make easy work of the Tigers, who have plenty of rebuilding to do before even thinking about sniffing for an upset. Alabama blows Missouri out of the water in this opener. Alabama 48, Missouri 10

College Football Top 25 Rankings: Alabama

— Written by Kevin McGuire, who is part of the Athlon Contributor Network. Follow him on Patreon, on Twitter @KevinOnCFB, on Instagram, and Like him on Facebook.