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5 College Football Picks Against the Spread (ATS) for Week 5

5 College Football Picks Against the Spread (ATS) for Week 5

5 College Football Picks Against the Spread (ATS) for Week 5

College football typically hits its stride in the month of October, but nothing is a given as we flip the calendars this week. A week after Oklahoma and LSU both took losses and Texas needed a major comeback to get past Texas Tech, will we get any crazy developments in what appears to be a pretty tame weekend of college football?

The SEC headlines this week's schedule with a pair of games between ranked opponents, and K.J. Costello and Mississippi State look to prove last week was not a fluke. Should you ride with the hot hand in Starkville, or is this a week to lay off and see how the Bulldogs follow up their upset of the defending national champions?

Note: All times are ET and all games are on Saturday, Oct. 3.

Alabama (-17.5) vs. Texas A&M, 3:30 p.m.

Nick Saban has yet to lose to any of his previous assistants, and that is a trend not worth betting against this weekend. Jimbo Fisher's Aggies looked pretty tame last weekend, although perhaps that was by design. Ever since losing to Johnny Manziel and his Heisman moment, Alabama has had little problem taking care of the Aggies. Again, follow the trends. Alabama 38, Texas A&M 20

College Football Top 25 Rankings: Alabama

Auburn (+6.5) at Georgia, 7:30 p.m.

Crazy things happen when Auburn and Georgia get together, so embrace the silliness that is about to unfold this weekend under the lights in Athens. Bo Nix and the Tigers will have their work cut out for them against the Bulldog defense, but Georgia could also have some trouble scoring much. Auburn keeps this one close, and may just leave with a major win in the SEC. Auburn 24, Georgia 23

College Football Top 25 Rankings: Auburn

Mississippi State (-18) vs. Arkansas, 7:30 p.m.

Sure, Arkansas led Georgia in a defensive battle for a half last week, but K.J. Costello was busy rewriting the SEC single-game passing record in his Mississippi State debut. Should you expect more of the big air stats from the Stanford transfer as Mike Leach coaches his first game in Starkville? They don't call it Stark Vegas without reason. Roll with the hot hand. Mississippi State 38, Arkansas 17

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College Football Top 25 Rankings: Mississippi State

Iowa State (+7) vs. Oklahoma, 7:30 p.m.

It is very tempting to take Oklahoma in a big way as the Sooners look to rebound from last week's stunning loss at home to Kansas State. And doing so may be the safe move because it would be nearly impossible to recover in the College Football Playoff hunt with a second loss if the Sooners get tripped up again. But playing on the road against Brock Purdy and the Cyclones isn't exactly the best spot for a Sooners squad looking to bounce back. Oklahoma gets the win, but Iowa State makes them earn it. Oklahoma 33, Iowa State 31

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LSU (-20) at Vanderbilt, 7:30 p.m.

Speaking of bouncing back, LSU is looking to even its record after a stunning loss to Mississippi State in its season opener. Playing Vanderbilt regardless of location is as good as it gets for a team like the Tigers looking for a rebound. LSU waltzes its way to a win in Nashville. LSU 32, Vanderbilt 9

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Last week: 1-4
Season: 9-13

Podcast: CFB Week 5 Preview + Predictions

— Written by Kevin McGuire, who is part of the Athlon Contributor Network. Follow him on Patreon, on Twitter @KevinOnCFB, on Instagram, and Like him on Facebook.