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College Football Picks: Expert Predictions for Every Game in Week 2

College football's Week 2 slate for the 2022 season features 82 games, and our NCAA experts are ready with their predictions and picks.

The Week 2 action begins on Friday night with two games, as New Mexico hosts Boise State and Louisville takes on UCF. The first wave of games on Saturday features Alabama-Texas, South Carolina-Arkansas, Wake Forest-Vanderbilt, Missouri-Kansas State, North Carolina-Georgia State and UTSA-Army. The afternoon window includes Washington State-Wisconsin, Tennessee-Pitt, Colorado-Air Force, Houston-Texas Tech, Iowa State-Iowa and Virginia-Illinois. The first night slate includes Kentucky-Florida, USC-Stanford, Arizona State-Oklahoma State, and Boston College-Virginia Tech. The late-night window features a high-profile showdown between Baylor and BYU, Oregon State visiting Fresno State and Mississippi State taking on Arizona.

Each week, Athlon Sports’ editors will pick every game in the FBS ranks. Follow us on Twitter: (@AthlonSports)

College Football Picks: Expert Predictions for Every Game in Week 2

Steven LassanMark RossBen Weinrib

Louisville at UCF (Fri.)

UCF

UCF

UCF

Boise State at New Mexico (Fri.)

Boise State

Boise State

Boise State

Arkansas State at Ohio State

Ohio State

Ohio State

Ohio State

Southern Miss at Miami

Miami

Miami

Miami

Wake Forest at Vanderbilt

Wake Forest

Wake Forest

Wake Forest

Ohio at Penn State

Penn State

Penn State

Penn State

Western Illinois at Minnesota

Minnesota

Minnesota

Minnesota

UTSA at Army

UTSA

Army

UTSA

Duke at Northwestern

Northwestern

Northwestern

Northwestern

Missouri at Kansas State

Kansas State

Kansas State

Kansas State

North Carolina at Georgia State

North Carolina

North Carolina

North Carolina

Charleston Southern at NC State

NC State

NC State

NC State

South Alabama at Central Michigan

Central Michigan

South Alabama

Central Michigan

Southern Utah at Utah

Utah

Utah

Utah

Western Michigan at Ball State

Western Michigan

WMU

WMU

Lafayette at Temple

Temple

Temple

Temple

Marshall at Notre Dame

Notre Dame

Notre Dame

Notre Dame

Furman at Clemson

Clemson

Clemson

Clemson

Washington State at Wisconsin

Wisconsin

Wisconsin

Wisconsin

Kennesaw State at Cincinnati

Cincinnati

Cincinnati

Cincinnati

Memphis at Navy

Memphis

Memphis

Memphis

Colorado at Air Force

Air Force

Air Force

Air Force

Maryland at Charlotte

Maryland

Maryland

Maryland

Samford at Georgia

Georgia

Georgia

Georgia

Akron at Michigan State

Michigan State

Michigan State

Michigan State

Houston at Texas Tech

Houston

Houston

Texas Tech

Middle Tennessee at Colorado State

Colorado State

Colorado State

Colorado State

Norfolk State at James Madison

James Madison

James Madison

James Madison

Portland State at Washington

Washington

Washington

Washington

Northern Colorado at Wyoming

Wyoming

Wyoming

Wyoming

Indiana State at Purdue

Purdue

Purdue

Purdue

Virginia at Illinois

Virginia

Virginia

Virginia

Eastern Kentucky at Bowling Green

Bowling Green

Bowling Green

Bowling Green

Wagner at Rutgers

Rutgers

Rutgers

Rutgers

UNLV at California

California

California

California

Alabama State at UCLA

UCLA

UCLA

UCLA

UIW at Nevada

Nevada

Nevada

Nevada

Kansas at West Virginia

West Virginia

West Virginia

West Virginia

UAB at Liberty

UAB

UAB

UAB

Gardner-Webb at Coastal Carolina

Coastal Carolina

Coastal Carolina

Coastal Carolina

Holy Cross at Buffalo

Buffalo

Buffalo

Buffalo

SE Louisiana at Florida Atlantic

FAU

FAU

FAU

Old Dominion at East Carolina

East Carolina

East Carolina

East Carolina

Robert Morris at Miami (Ohio)

Miami (Ohio)

Miami (Ohio)

Miami (Ohio)

Kent State at Oklahoma

Oklahoma

Oklahoma

Oklahoma

Central Arkansas at Ole Miss

Ole Miss

Ole Miss

Ole Miss

Stephen F. Austin at Louisiana Tech

Louisiana Tech

Louisiana Tech

Louisiana Tech

UMass at Toledo

Toledo

Toledo

Toledo

Western Carolina at Georgia Tech

Georgia Tech

Georgia Tech

Georgia Tech

Northern Illinois at Tulsa

Tulsa

Northern Illinois

Tulsa

Lamar at SMU

SMU

SMU

SMU

FIU at Texas State

Texas State

Texas State

Texas State

Eastern Michigan at Louisiana

Louisiana

Louisiana

Louisiana

Alcorn State at Tulane

Tulane

Tulane

Tulane

Howard at USF

USF

USF

USF

Alabama A&M at Troy

Troy

Troy

Troy

Syracuse at UConn

Syracuse

Syracuse

Syracuse

Weber State at Utah State

Utah State

Utah State

Utah State

Arizona State at Oklahoma State

Oklahoma State

Oklahoma State

Oklahoma State

USC at Stanford

USC

USC

USC

San Jose State at Auburn

Auburn

Auburn

Auburn

McNeese at Rice

Rice

Rice

Rice

Georgia Southern at Nebraska

Nebraska

Nebraska

Nebraska

Texas Southern at North Texas

North Texas

North Texas

North Texas

Southern at LSU

LSU

LSU

LSU

Hawaii at Michigan

Michigan

Michigan

Michigan

Tarleton State at TCU

TCU

TCU

TCU

Nicholls at ULM

ULM

ULM

ULM

Boston College at Virginia Tech

Virginia Tech

Boston College

Virginia Tech

Idaho at Indiana

Indiana

Indiana

Indiana

Idaho State at San Diego State

San Diego State

San Diego State

San Diego State

Eastern Washington at Oregon

Oregon

Oregon

Oregon

New Mexico State at UTEP

UTEP

UTEP

UTEP

Oregon State at Fresno State

Oregon State

Oregon State

Fresno State

Appalachian State at Texas A&M

Texas A&M

Texas A&M

Texas A&M

Mississippi State at Arizona

Mississippi State

Arizona

Mississippi State

South Carolina at Arkansas

Arkansas

Arkansas

Arkansas

Iowa State at Iowa

Iowa

Iowa

Iowa

Baylor at BYU

Baylor

Baylor

Baylor

Tennessee at Pitt

Tennessee

Tennessee

Pitt

Kentucky at Florida

Florida

Florida

Kentucky

Alabama at Texas

Alabama

Alabama

Alabama

Podcast: Complete Week 2 Preview, Predictions and Picks Against the Spread