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College Football Picks: Expert Predictions for Every Game in Week 3

College football's Week 3 slate for the 2022 season features 72 games, and our NCAA experts are ready with their predictions and picks.

The Week 3 slate begins on Friday night with Florida State at Louisville and Air Force at Wyoming. The first wave of games on Saturday features Georgia-South Carolina, Oklahoma-Nebraska, Purdue-Syracuse, and WKU-Indiana. The afternoon slate includes California-Notre Dame, BYU-Oregon, Penn State-Auburn, and Kansas-Houston. Mississippi State-LSU headlines the early evening matchups, along with Texas Tech-NC State, Michigan State-Washington, USF-Florida, SMU-Maryland, and UTSA-Texas. The late slate of games features Miami-Texas A&M, San Diego State-Utah, Fresno State-USC, and North Dakota State-Arizona.

Each week, Athlon Sports’ editors will pick every game in the FBS ranks. Follow us on Twitter: (@AthlonSports)

College Football Picks: Expert Predictions for Every Game in Week 3

Steven LassanMark RossBen Weinrib

Florida State at Louisville (Fri.)

Florida State

Florida State

Florida State

Air Force at Wyoming (Fri.)

Air Force

Air Force

Air Force

Wofford at Virginia Tech

Virginia Tech

Virginia Tech

Virginia Tech

UConn at Michigan

Michigan

Michigan

Michigan

Youngstown State at Kentucky

Kentucky

Kentucky

Kentucky

Texas State at Baylor

Baylor

Baylor

Baylor

Abilene Christian at Missouri

Missouri

Missouri

Missouri

Villanova at Army

Army

Army

Army

Southern Illinois at Northwestern

Northwestern

Northwestern

Northwestern

Purdue at Syracuse

Purdue

Purdue

Purdue

Cincinnati vs. Miami (Ohio) (Cincinnati)

Cincinnati 

Cincinnati

Cincinnati

LIU at Kent State

Kent State

Kent State

Kent State

WKU at Indiana

Indiana

Indiana

WKU

Towson at West Virginia

West Virginia

West Virginia

West Virginia

Buffalo at Coastal Carolina

Coastal Carolina

Coastal Carolina

Coastal Carolina

Bucknell at Central Michigan

Central Michigan

Central Michigan

Central Michigan

South Alabama at UCLA

UCLA

UCLA

UCLA

Ohio at Iowa State

Iowa State

Iowa State

Iowa State

Rutgers at Temple

Rutgers

Rutgers

Rutgers

Old Dominion at Virginia

Virginia

Virginia

Virginia

Murray State at Ball State

Ball State

Ball State

Ball State

California at Notre Dame

Notre Dame

Notre Dame

Notre Dame

Tulane at Kansas State

Kansas State

Kansas State

Kansas State

North Texas at UNLV

UNLV

UNLV

North Texas

Ole Miss at Georgia Tech

Ole Miss

Ole Miss

Ole Miss

Vanderbilt at Northern Illinois

Vanderbilt

Vanderbilt

Vanderbilt

Colorado at Minnesota

Minnesota

Minnesota

Minnesota

New Mexico State at Wisconsin

Wisconsin

Wisconsin

Wisconsin

Stony Brook at UMass

UMass

UMass

UMass

Troy at Appalachian State

Appalachian State

Appalachian State

Appalachian State

Georgia Southern at UAB

UAB

UAB

UAB

ULM at Alabama

Alabama

Alabama

Alabama

Kansas at Houston

Houston

Kansas

Houston

UT Martin at Boise State

Boise State

Boise State

Boise State

Liberty at Wake Forest

Wake Forest

Wake Forest

Wake Forest

Colorado State at Washington State

Washington State

Washington State

Washington State

Marshall at Bowling Green

Marshall

Marshall

Marshall

North Carolina A&T at Duke

Duke

Duke

Duke

Campbell at East Carolina

East Carolina

East Carolina

East Carolina

Toledo at 3 Ohio State

Ohio State

Ohio State

Ohio State

Arkansas-Pine Bluff at Oklahoma State

Oklahoma State

Oklahoma State

Oklahoma State

Missouri State at Arkansas

Arkansas

Arkansas

Arkansas

Akron at Tennessee

Tennessee

Tennessee

Tennessee

Jacksonville State at Tulsa

Tulsa

Tulsa

Tulsa

Northwestern State at Southern Miss

Southern Miss

Southern Miss

Southern Miss

Arkansas State at Memphis

Memphis

Memphis

Memphis

Charlotte at Georgia State

Georgia State

Georgia State

Georgia State

Tennessee State at Middle Tennessee

Middle Tennessee

Middle Tennessee

Middle Tennessee

USF at Florida

Florida

Florida

Florida

Pitt at Western Michigan

Pitt

Pitt

Pitt

Nevada at Iowa

Iowa

Iowa

Iowa

SMU at Maryland

Maryland

Maryland

SMU

Maine at Boston College

Boston College

Boston College

Boston College

UCF at Florida Atlantic

UCF

UCF

UCF

Louisiana at Rice

Louisiana

Louisiana

Louisiana

Louisiana Tech at Clemson

Clemson

Clemson

Clemson

Montana State at Oregon State

Oregon State

Oregon State

Oregon State

UTEP at New Mexico

UTEP

UTEP

San Diego State at Utah

Utah

Utah

Utah

Fresno State at USC

USC

USC

USC

North Dakota State at Arizona

Arizona

North Dakota State

North Dakota State

Eastern Michigan at Arizona State

Arizona State

Arizona State

Arizona State

Duquesne at Hawaii

Hawaii

Hawaii

Hawaii

Texas Tech at NC State

NC State

NC State

NC State

Michigan State at Washington

Washington

Washington

Michigan State

UTSA at Texas

Texas

Texas

Texas

Oklahoma at Nebraska

Oklahoma

Oklahoma

Oklahoma

Penn State at Auburn

Penn State

Penn State

Penn State

Georgia at South Carolina

Georgia

Georgia

Georgia

Mississippi State at LSU

Mississippi State

LSU

LSU

BYU at Oregon

Oregon

Oregon

BYU

Miami at Texas A&M

Texas A&M

Texas A&M

Texas A&M

Podcast: Week 3 Predictions and Preview + Betting Tips and Picks Against the Spread