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College Football Picks: Expert Predictions for Every Game in Week 4

College football's Week 4 slate for the 2021 season features 67 games, and our NCAA experts are ready with their predictions and picks. The Week 4 slate starts on Thursday night with Appalachian State hosting Marshall and continues on Friday with four games, including Wake Forest-Virginia and Liberty-Syracuse. The first wave of games on Saturday features Georgia-Vanderbilt, Notre Dame-Wisconsin (in Chicago), LSU-Mississippi State, SMU-TCU, and Missouri-Boston College. The afternoon slate kicks off with an SEC battle between Texas A&M and Arkansas in Arlington, Texas, along with Rutgers-Michigan, Clemson-NC State, Louisville-Florida State, and UTSA-Memphis. The first window of night games includes Tennessee-Florida, Nebraska-Michigan State, Kentucky-South Carolina, and West Virginia-Oklahoma. Arizona-Oregon, California-Washington, Oregon State-USC, and Colorado-Arizona State headline the late-night window of top games for Week 4.

Each week, Athlon Sports’ editors will pick every game in the FBS ranks. Follow us on Twitter: (@AthlonSports)

College Football Picks: Expert Predictions for Every Game in Week 4

Steven LassanMark RossBen Weinrib

Marshall at Appalachian State (Thurs.)

Appalachian State

Appalachian State

Appalachian State

Middle Tennessee at Charlotte (Fri.)

Charlotte

Charlotte

Charlotte

Wake Forest at Virginia (Fri.)

Virginia

Wake Forest

Virginia

Liberty at Syracuse (Fri.)

Liberty

Liberty

Liberty

UNLV at Fresno State (Fri.)

Fresno State

Fresno State

Fresno State

Miami (Ohio) at Army

Army

Army

Army

Missouri at Boston College

Missouri

Missouri

Boston College

FIU at Central Michigan

Central Michigan

Central Michigan

Central Michigan

Villanova at Penn State

Penn State

Penn State

Penn State

New Hampshire at Pitt

Pitt

Pitt

Pitt

Wagner at Temple

Temple

Temple

Temple

Richmond at Virginia Tech

Virginia Tech

Virginia Tech

Virginia Tech

Bowling Green at Minnesota

Minnesota

Minnesota

Minnesota

Ohio at Northwestern

Northwestern

Northwestern

Northwestern

Georgia at Vanderbilt

Georgia

Georgia

Georgia

Boise State at Utah State

Boise State

Boise State

Boise State

Central Connecticut State at Miami

Miami

Miami

Miami

UMass at Coastal Carolina

Coastal Carolina

Coastal Carolina

Coastal Carolina

Toledo at Ball State

Toledo

Toledo

Toledo

Texas State at Eastern Michigan

Eastern Michigan

Eastern Michigan

Eastern Michigan

San Jose State at Western Michigan

San Jose State

San Jose State

Western Michigan

Maine at Northern Illinois

Northern Illinois

Northern Illinois

Northern Illinois

Washington State at Utah

Utah

Utah

Utah

Wyoming at UConn

Wyoming

Wyoming

Wyoming

Louisville at Florida State

Louisville

Louisville

Louisville

Kent State at Maryland

Maryland

Maryland

Maryland

Rutgers at Michigan

Michigan

Michigan

Michigan

Illinois at Purdue

Purdue

Purdue

Purdue

Iowa State at Baylor

Iowa State

Iowa State

Iowa State

Colorado State at Iowa

Iowa

Iowa

Iowa

UTSA at Memphis

Memphis

UTSA

Memphis

Towson at San Diego State

San Diego State

San Diego State

San Diego State

Kansas at Duke

Duke

Kansas

Duke

Georgia State at Auburn

Auburn

Auburn

Auburn

Arkansas State at Tulsa

Tulsa

Tulsa

Tulsa

Charleston Southern at East Carolina

East Carolina

East Carolina

East Carolina

Louisiana at Georgia Southern

Louisiana

Louisiana

Louisiana

Buffalo at Old Dominion

Buffalo

Buffalo

Buffalo

Texas Southern at Rice

Rice

Rice

Rice

Nebraska at Michigan State

Michigan State

Michigan State

Michigan State

Kentucky at South Carolina

Kentucky

Kentucky

Kentucky

Navy at Houston

Houston

Houston

Houston

North Texas at Louisiana Tech

Louisiana Tech

Louisiana Tech

Louisiana Tech

Kansas State at Oklahoma State

Oklahoma State

Oklahoma State

Oklahoma State

North Carolina at Georgia Tech

North Carolina

North Carolina

North Carolina

Akron at Ohio State

Ohio State

Ohio State

Ohio State

Southern Miss at Alabama

Alabama

Alabama

Alabama

Troy at ULM

Troy

Troy

Troy

UAB at Tulane

Tulane

Tulane

Tulane

Indiana at WKU

Indiana

Indiana

Indiana

Florida Atlantic at Air Force

Air Force

Air Force

Florida Atlantic

Hawaii at New Mexico State

Hawaii

Hawaii

Hawaii

New Mexico at UTEP

New Mexico

UTEP

UTEP

California at Washington

Washington

Washington

Washington

USF at BYU

BYU

BYU

BYU

Colorado at Arizona State

Arizona State

Arizona State

Arizona State

Arizona at Oregon

Oregon

Oregon

Oregon

Oregon State at USC

USC

USC

USC

Notre Dame vs. Wisconsin (Chicago)

Notre Dame

Notre Dame

Wisconsin

Texas A&M vs. Arkansas (Arlington, Texas)

Texas A&M

Texas A&M

Texas A&M

LSU at Mississippi State

LSU

LSU

LSU

SMU at TCU

TCU

TCU

TCU

West Virginia at Oklahoma

Oklahoma

Oklahoma

Oklahoma

Tennessee at Florida

Florida

Florida

Florida

Clemson at NC State

Clemson

Clemson

Clemson

UCLA at Stanford

UCLA

UCLA

UCLA

Texas Tech at Texas

Texas

Texas

Texas

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