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College Football Upset Watch for Week 2

These favored teams could find themselves on the wrong end of the scoreboard this Saturday.

Welcome to Week 2 of the College Football Upset Watch here at Athlon Sports!

Related: College Football Predictions for Every Game in Week 2

Last week, we saw one of the teams who was put on "upset watch" — Virginia Tech — fall to Old Dominion. Who will it be this week?

Let's take a look at the five teams on "upset watch" for Week 2.

No. 10 USC (at Stanford)

There's a lot of hype surrounding the No. 10 USC Trojans right now, even though they haven't faced a serious test.

The Trojans are favored by single digits heading into this weekend's game against Stanford. That's not the kind of confidence USC fans want to see from oddsmakers and bettors when a top-10 team takes on an unranked foe.

Then again, not many unranked teams have a future NFL quarterback on the roster as Stanford does in Tanner McKee. The Cardinal's ability to move the ball is going to make this one very interesting.

No. 11 Oklahoma State (vs. Arizona State)

The Cowboys have their sights set on another run to the Big 12 Championship Game and a possible appearance in another New Year's Six bowl. First, they'll need to get past an Arizona State team that features Florida transfer Emory Jones at quarterback, some skill players who cause matchup problems, and a defense with a couple of future 2023 NFL Draft picks roaming around.

This is a possible season-defining game for Arizona State and a huge trap game for the Cowboys.

No. 16 Arkansas (vs. South Carolina)

The Razorbacks moved up in the AP poll following their win over Cincinnati last week. That victory looked great on the ticker and resulted in a bump up three spots in the rankings. Anyone who actually watched that game, however, knows that it wasn't anything remotely close to a win over the Cincinnati team that made it to the College Football Playoff last season.

Now the Razorbacks open SEC play by hosting the South Carolina Gamecocks, who sleepwalked through a win 35-14 win over Georgia State last week. South Carolina will have Oklahoma transfer Spencer Rattler under center. These are the kinds of games he came to the SEC to play. There's no pressure on the visiting Gamecocks.

No. 23 Wake Forest (at Vanderbilt)

The Demon Deacons are probably feeling pretty good coming to Nashville ranked No. 23 in the country after a blowout win over VMI to start the year. They are favored by nearly two touchdowns with the return of quarterback Sam Hartman from a blood clot issue and expect to be a factor in the race for the ACC title this season.

On the other side of the field is a Vanderbilt team led by one of the most underrated dual-threat quarterbacks in the country in Mike Wright. With Wright under center, the Commodores have scored a total of 105 points in their first two games of the 2022 season. Not bad for a team coached by a defensive guru in Clark Lea. 

Something's cooking in Nashville, and Wake Forest is next in line for a taste.

Nebraska (vs. Georgia Southern)

After stumbling out of the gates in Ireland by losing to Northwestern on the back of some head-scratching plays and coaching decisions, the Huskers didn't look a whole lot better last week through the first three-quarters of a slap fight with unranked FCS foe North Dakota. Nebraska eventually pulled away in the fourth quarter, but not before raising the blood pressure of their collective fan base for most of the game.

This weekend, Nebraska welcomes in a Georgia Southern team led by former USC head coach Clay Helton. The Eagles opened their 2022 campaign by dispatching an FCS foe of their own, defeating Morgan State 59-7.

Nebraska is favored by more than three touchdowns in this one, which is interesting. There were times when Nebraska's supposed talent gap was not apparent against North Dakota last weekend. Georgia Southern is much more talented than North Dakota — especially in the trenches.

It could be another nerve-wracking Saturday in Lincoln for the Sea of Red.

Podcast: Complete Week 2 Preview, Predictions and Picks Against the Spread

— Written by J.P. Scott, who is part of the Athlon Contributor Network. His work has appeared on,, Yahoo! SBNation and Bleacher Report. He is a three-time FWAA writing contest award winner. Follow him on Twitter @TheJPScott.