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College Football Upset Watch for Week 4

Michigan, BYU and Appalachian State better be wary of the teams they are hosting on Saturday.

Welcome to Week 4 of the college football "Upset Watch" here at Athlon Sports!

We're starting to see a pattern, as we've had at least one team from each of the first three weeks of "upset watch" go down to underdogs. Last week, it was Houston losing to Kansas. Who will it be this week?

Related: College Football Predictions for Every Game in Week 4

Let's take a look at the five teams on "upset watch" for Week 4.

Note: All games are on Saturday, Sept. 24 and times are ET.

No. 4 Michigan (vs. Maryland)

12 p.m. on FOX, live stream on fuboTV (Start your free trial)

Because of a notoriously weak schedule to open the season, we really don't know how good this Michigan team is. What we do know is that Maryland returned a bunch of starters from last season and has yet to lose in 2022. This will be the Wolverines' first real challenge of the year. The Terrapins and head coach Mike Locksley are playing with house money in this one. All pressure is on Jim Harbaugh's crew to stay unbeaten and keep pace with Ohio State in the Big Ten East.

No. 5 Clemson (at No. 21 Wake Forest)

12 p.m. on ABC, live stream on fuboTV (Start your free trial)

Clemson hasn't looked like the Clemson we're used to seeing since Trevor Lawrence left. It's the honest truth, but the pollsters continue to give Dabo Swinney's team the benefit of the doubt. Now the Tigers travel to Winston-Salem to face a Demon Deacons team breathing a sigh of relief after nearly losing at home to Liberty. Good teams find ways to win close games, and Wake Forest survived the kind of scare that could set the tone for the season. Now the Deacons play their biggest regular-season game with a renewed energy and focus (and quarterback Sam Hartman at the helm). Clemson will want to keep one eye on the exit.

No. 19 BYU (vs. Wyoming)

10:15 p.m. on ESPN2, live stream on fuboTV (Start your free trial)

BYU was simply outmanned last week against Oregon and possibly even exposed. Wyoming — on the other hand — took down an Air Force team that was collecting a lot of passengers on its bandwagon to start the year. The Falcons are not an easy team to prepare for. In that regard, BYU gives Wyoming a more straightforward and traditional week of film prep. If both teams play with the same level of execution and energy as they did last week, the Cowboys will win this game despite the host Cougars being favored by more than three touchdowns.

Iowa (at Rutgers)

7 p.m. on FS1, live stream on fuboTV (Start your free trial)

It's not that Rutgers has looked good, but the Scarlet Knights haven't lost. And if you follow college football at all, you know how Iowa has struggled on offense. Rutgers is going to score points, even against a good Hawkeyes defense. Knights head coach Greg Schiano is good enough to figure out how to do what every other team Iowa has played so far has done: make the offense look bad. If you like fist fights, this might be your must-watch game this week.

Appalachian State (vs. James Madison)

3:30 p.m. on ESPN+

One of the historical darlings and juggernauts of the Group of 5 ranks, Appalachian State, will have its work cut out when James Madison comes to Boone. The Dukes have been one of the premier FCS programs in recent years and are seemingly poised to make an immediate splash at the FBS level. The raucous road environment won't be a factor. James Madison has played in bigger games with a lot more meaning. The Dukes have the talent and the coaching to pull off the upset of an Appalachian State team whose first three games have been decided by a total of nine points.

Podcast: Week 4 Preview, Predictions and Picks Against the Spread

— Written by J.P. Scott, who is part of the Athlon Contributor Network. His work has appeared on,, Yahoo! SBNation and Bleacher Report. He is a three-time FWAA writing contest award winner. Follow him on Twitter @TheJPScott.