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Ohio State Football: Game-By-Game Predictions for 2022

Ohio State Buckeyes Football

Challenges can be found throughout the Buckeyes' 2022 schedule but most of those games will be played at home.

Ohio State went 11-2 in 2021, with a comeback Rose Bowl win over Pac-12 champion Utah. And in Columbus, the feeling was one of disappointment.

For the first time in Ryan Day's tenure as head coach, Ohio State did not win the Big Ten or qualify for the College Football Playoff. The most bitter feeling of all was losing on the road at Michigan, "That Team Up North," for the first time since 2011.

Day has used the pain of the 2021 season to motivate his squad for the upcoming campaign. Recognizing Ohio State's defensive issues, Day completely overhauled the defensive staff, bringing in Jim Knowles as defensive coordinator/linebackers coach, Perry Eliano as safeties coach, and former Buckeye Tim Walton as cornerbacks coach. Day also hired Justin Frye to replace Greg Studrawa as offensive line coach, identifying a need for the Buckeyes to get back to a more physical style of play along the offensive line with the running game.

Related: Ohio State Football: 2022 Buckeyes Season Preview and Prediction

Will the changes be enough for Ohio State to get back to its traditional perch among the upper echelon of college football's elite programs in 2022? Below are the thoughts of some of the experts at Athlon Sports as they review the Buckeyes' upcoming schedule.

Ohio State Football Game-by-Game Predictions for 2022

Steven LassanMark RossChip Minnich

Notre Dame

Ohio State

Ohio State

Ohio State

Arkansas State

Ohio State

Ohio State

Ohio State

Toledo

Ohio State

Ohio State

Ohio State

Wisconsin

Ohio State

Ohio State

Ohio State

Rutgers

Ohio State

Ohio State

Ohio State

at Michigan State

Ohio State

Ohio State

Ohio State

Iowa

Ohio State

Ohio State

Ohio State

at Penn State

Ohio State

Ohio State

Ohio State

at Northwestern

Ohio State

Ohio State

Ohio State

Indiana

Ohio State

Ohio State

Ohio State

at Maryland

Ohio State

Ohio State

Ohio State

Michigan

Ohio State

Ohio State

Ohio State

Final Record

12-0

12-0

12-0

Steven Lassan (@AthlonSteven)
The odds always favor every team in college football stumbling once during the regular season, but it’s hard to find a spot for a loss on Ohio State’s 2022 slate. Perhaps at Michigan State or Penn State? Maybe Michigan? I expect the Buckeyes to be favored in two of those games by at least double digits. And even though the Wolverines won last year, considering the personnel losses in Ann Arbor and the fact that this game will be played in Columbus, Ohio State should be favored to win this time around.

Coach Ryan Day’s squad doesn’t have many glaring weaknesses, and the arrival of new assistants Justin Frye (OL) and defensive coordinator Jim Knowles will solidify two areas of concern from ’21. Scoring points won’t be a problem behind quarterback C.J. Stroud, running back TreVeyon Henderson, and the nation’s No. 1 receiving corps and offensive line. But getting stops and overall defensive play were the primary culprits in Ohio State's two losses last year. Talent isn’t a concern, so it’s all about how fast Knowles can get this unit back on track. The guess here is the Buckeyes continue their high-scoring ways on offense and improve on defense enough to book a trip to the national championship game in January.

Mark Ross (@AthlonMarkR)
At first glance, Ohio State's schedule is too difficult to envision the Buckeyes going undefeated. But when the games against Michigan, Notre Dame, Wisconsin and Iowa all happen at home then it's easier to see Ryan Day's team running the table. Yes, the opener against the Fighting Irish won't be easy but I give the edge to C.J. Stroud and the offense even if the new-look defense under coordinator Jim Knowles isn't quite ready. Road dates with Michigan State and Penn State can't be taken lightly but by that time I expect Knowles to have his defense on the same page while Stroud and company continue to put up points in bunches. Everyone knows the most important game is the last one but again it's at home and all that needs to be said about that one is 42-27. It won't be easy but I like Ohio State's chances of running the table on its way to Indianapolis and more than likely, the College Football Playoff.

Chip Minnich (@ChipMinnich)
If Ohio State has one advantage to its arduous schedule in 2022, it is that most of the tough games are at home. Notre Dame, Wisconsin, Iowa, Michigan — all teams capable of defeating Ohio State, but all must come to Columbus to do so. Yes, Ohio State goes on the road to Michigan State, Penn State, and Maryland, all decent teams, but the Buckeyes have been able to handle the formidable road atmospheres at those places in recent seasons and should be able to do so again in 2022.

If the game at Penn State was a night game on Oct. 29, with the "White Out" conditions, I would be likely to pick that game as an Ohio State loss; the kickoff time has not been announced yet, but it seems likely to be a noon ET game. Even with the challenges of going undefeated, I have a difficult time finding the loss on the schedule for the Buckeyes. I see an undefeated Ohio State ready to rumble at high noon on FOX with the Wolverines for the Big Ten East title on Nov. 26, and the Buckeyes heading back to Indianapolis to reclaim another Big Ten championship.

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