It shouldn't be a surprise that by this point into Week 5, we still don't know all the games that will be played and when. As of this writing, the Buffalo-Tennessee game has been tentatively moved to Tuesday (Tuesday Night Football!) and the Denver-New England game has been moved to Monday night.
It's no secret that COVID-19 has messed up everyone's life in some way or another, so it should not be a surprise that it's messing up football as well. With that being said, fantasy owners are going to have tough decisions to make. If you have any Bills or Titans, you will want to make sure that the game is going to take place before keeping them in your lineup. Hopefully by Sunday morning, we will all have a better idea about which games will be played, but be prepared for last-minute changes or cancellations (forfeits?).
Continue to start your best lineup; continue to play the waiver wire and look to make a trade. Watch the injury report and try to determine who might have a good week.
Please note 5 Up/5 Down is a guide on players that should exceed or fall below their rank this week. This is based on past performance, injury status, and matchup. This is not a start/sit column, but rather a guide.
Teams on bye: Detroit, Green Bay
Drew Brees, QB, New Orleans Saints
Brees plays best at home in primetime. While there may not be fans in the Superdome, it is still Brees' football home and that's where he's playing (unless something really crazy happens with Hurricane Delta) on Monday night. He's ranked No. 8 and he's a QB1 this week, but if he gets Michael Thomas back, he can certainly exceed that ranking. The Saints face the Chargers and that game has the potential to be a shootout. Brees has no issue passing deep to Thomas or short to Alvin Kamara. Either way, that translates to fantasy points. He has eight touchdown passes so far this season; expect that number to grow in Week 5.
Joshua Kelley, RB, Los Angeles Chargers
Austin Ekeler went down in Week 4 with a serious hamstring injury. He's been placed on injured reserve and both Kelley and Justin Jackson should step up in his absence. Kelley is ranked No. 23 for Week 5, but he should be the one to see the most work and exceed that ranking. He has been involved in the passing game, and that role should continue with Jackson handling more of the between-the-tackles work. Kelley does have a fumble in each of the past two games, so if he can hang on to the ball, the job is likely his.
Justin Jefferson, WR, Minnesota Vikings
In the past two weeks, Jefferson has two 100-yard games and a touchdown. He's starting to take on the role that Stefon Diggs played opposite Adam Thielen. In Week 5, the Vikings get to play the Seahawks, who allow the most fantasy points to opposing wide receivers. In two of the past four weeks, they have allowed multiple 100-yard receivers and in all four weeks, they have allowed at least one 100-yard receiver. It would not be surprising to find both Thielen and Jefferson with more than 100 yards at the end of Week 5. Jefferson is ranked No. 27 and should be a WR2.
JuJu Smith-Schuster, WR, Pittsburgh Steelers
After the unexpected bye in Week 4, the Steelers are back, facing the Eagles. Diontae Johnson is dealing with a toe injury but should play and this does eat into Smith-Schuster's targets, but he should still exceed his No. 31 ranking. He has three touchdowns so far on the season and the Eagles are a team that can be thrown on. Tyler Boyd had 125 yards in Week 3, and while Smith-Schuster may not quite reach that, he is a WR2.
Logan Thomas, TE, Washington Football Team
Washington has decided to bench Dwayne Haskins and start Kyle Allen against the Rams on Sunday. While it is unclear how this move will ultimately affect Thomas, typically when a quarterback first enters the game, they rely on their tight end. The Rams did allow three touchdowns to Bills tight ends in Week 3, and Thomas already has a touchdown this year. He's ranked No. 15, but if the Rams take away Terry McLaurin, Thomas can certainly exceed that.
Gardner Minshew, QB, Jacksonville Jaguars
After starting the season with back-to-back three-touchdown games, Minshew didn't throw a TD pass in Week 3. He got DJ Chark Jr. back in Week 4 and connected with him on two scoring strikes. The Jaguars face the Texans in Week 5 and it's another tough matchup. Houston hasn't allowed a quarterback to throw for more than 300 yards yet this season and have limited Lamar Jackson and Kirk Cousins to one TD pass. Ben Roethlisberger had two in Week 3 and Patrick Mahomes had three in Week 1. Minshew isn't at Mahomes' level and is a QB2, below his No. 11 ranking.
Kenyan Drake, RB, Arizona Cardinals
Drake had two games in the past two weeks where he was supposed to "break out" this year. Last year, Drake had some great games and fantasy owners drafted him for those again this year. He has one touchdown (in Week 1) and in Week 4, he finished with 35 rushing yards against a Panthers defense that can be run on. Instead, Chase Edmonds had 16 rushing yards but added five receptions for 24 yards and a touchdown. Drake is ranked No. 14, but with Edmonds out-performing him, this ranking is too high.
Jerick McKinnon, RB, San Francisco 49ers
McKinnon's No. 19 ranking may be about right if Raheem Mostert is still out. However, Mostert has returned to practice and is expected to play in Week 5. While that is still up in the air and it is hard to trust a player returning from injury, Mostert will likely take some of the work from McKinnon. While Mostert has been out, McKinnon has done well with touchdowns in the past three games. He also has been involved in the passing game – seven receptions for 43 yards in Week 4. His role is unclear at this point, but McKinnon is a very risky RB2.
Robert Woods, WR, Los Angeles Rams
In Week 1, Woods had more than 100 yards and it seemed he was going to be an every-week starter for fantasy owners, filling a WR2 slot. He followed that performance with two receptions for 14 yards in Week 2. He did get a touchdown in Week 3 before another down week against the Giants. The Rams face Washington in Week 5, which should have a similar game script as the game against the Giants. This means Woods will likely not reach his No. 14 ranking.
Tyler Higbee, TE, Los Angeles Rams
With Robert Woods in the “Down” list, it seems that a Rams pass catcher should find success. Don't expect it to be Higbee (spoiler alert: it just might be Cooper Kupp). Higbee had one great game this year (Week 2, where he had five receptions for 54 yards and three touchdowns). In the other three games, he didn't have more than three receptions or more than 40 yards and he didn't find the end zone. It's hard to trust Higbee at this point, although he certainly can get you a TD. He's a risky TE1, which is where he is ranked (No. 7).
Full Disclosure from Week 4
5 Up (1/5 correct)
Ryan Fitzpatrick, QB, Dolphins (Ranked: 15, Actual: 17)
Darrell Henderson Jr., RB, Rams (Ranked: 18, Actual: 46)
David Johnson, RB, Texans (Ranked: 22, Actual: 23)
DeVante Parker, WR, Dolphins (Ranked: 25, Actual: 12)
Rob Gronkowski, TE, Buccaneers (Ranked: 23, Actual: 37)
5 Down (3/4 correct)
Cam Newton, QB, Patriots (Ranked: 10, Actual: DNP/COVID-19)
Austin Ekeler, RB, Chargers (Ranked: 14, Actual: 64)
Stefon Diggs, WR, Bills (Ranked: 11, Actual: 17)
Terry McLaurin, WR, Washington (Ranked: 12, Actual: 10)
Mike Gesicki, TE, Dolphins (Ranked: 4, Actual: 44)
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.