On Saturday, the Colts announced that Jacoby Brissett, despite practicing this week, would be out for Week 10. Odds are the team thinks they can beat the Dolphins with Brian Hoyer and let Brissett have an extra week of rest. Other than Brissett, Cam Newton went on injured reserve this week, but no other quarterbacks have been ruled out for Week 10. Fantasy owners can enjoy having Patrick Mahomes back in their lineup. Six teams are on a bye an there are a few quarterback injuries to keep an eye on this week.
Running backs that have been ruled out include James Conner, Chase Edmonds, Ito Smith, and Benny Snell. Alvin Kamara should return for New Orleans, David Johnson is expected back for Arizona, and fire up the Steelers' Jaylen Samuels as an RB2 with upside because Conner and Snell are both out and his likely involvement in the short passing game. Here's the scoop on the wide receiver and tight end injuries you need to keep an eye on. And as always, be sure to check the inactive report before game time.
Teams on bye: Denver, Houston, Jacksonville, New England, Philadelphia, Washington
Note: All times are ET and all games are on Sunday, Nov. 10, unless otherwise noted.
Lamar Jackson (illness), QB, Baltimore Ravens at Cincinnati Bengals, 1 p.m.
Jackson missed practice on Thursday with an illness, but he returned on Friday. Rarely do illnesses keep a player off the field for a game, and this is no exception. Fantasy owners should expect to have Jackson who is a QB1 against the Bengals. In a tough Week 9 matchup against the NFL's No. 1 defense, he threw for a touchdown and ran two in himself. Against the Bengals, he's a must-start.
Matthew Stafford (hip/back), QB, Detroit Lions at Chicago Bears, 1 p.m.
At this point in the season, Stafford is banged up. It's been a while since the Lions' bye and Stafford has been throwing the ball a ton. He's expected to play against the Bears, but it is a tough matchup for him. The Bears have only allowed one quarterback to throw for more than 300 yards. They haven't allowed a quarterback to throw for more than two touchdowns. Stafford will likely play, but he's a QB2.
Le'Veon Bell (knee), RB, New York Jets vs. New York Giants, 1 p.m.
Bell had an MRI on Monday and it came out clean. However, he didn't practice on Wednesday. Bell was a limited participant on Thursday and Friday and received the questionable tag, but the Jets seem to think that he will play in Week 10. It's a good matchup, but it's hard to trust someone who is clearly banged up. In Week 9, he ran for 66 yards and caught eight passes for 55 yards. If active, he's an RB2.
Matt Breida (ankle), RB, San Francisco 49ers vs. Seattle Seahawks, 8:15 p.m. (Mon.)
Breida was questionable heading into Week 9 with the same ankle injury. He was able to play through it and put in limited practices all week. In Week 9, he had 78 rushing yards and two receptions for 14 yards. While the 49ers don't play until Monday night, fantasy owners should expect to have Breida again. He's an RB2 as Tevin Coleman will be in the mix as well. Raheem Mostert also is questionable with a knee injury, but fantasy owners shouldn't plan on using him.
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.