For Week 12, the focus for fantasy owners is not necessarily injuries (or turkey and pumpkin pie), but rather COVID-19. The Ravens/Steelers game has already been postponed twice and is tentatively scheduled for Tuesday night. Keep an eye on those players as there seem to be more and more positives each day (James Conner tested positive and may be out as well).
For other teams, there are more players that either tested positive for COVID-19 or need to quarantine as they were in close contact with someone with COVID-19. For example, Denver won't even have an NFL quarterback on its active roster on Sunday. More than ever, be sure to check the team’s inactive reports to make sure that your players are all active.
Salvon Ahmed, RB, Miami Dolphins
John Brown, WR, Buffalo Bills
Rex Burkhead, RB, New England Patriots
Tevin Coleman, RB, San Francisco 49ers
Chris Conley, WR, Jacksonville Jaguars
D.J. Chark, WR, Jacksonville Jaguars
Todd Gurley, RB, Atlanta Falcons
Adam Humphries, WR, Tennessee Titans
Drew Lock, QB, Denver Broncos
Christian McCaffrey, RB, Carolina Panthers
Ty Montgomery, RB, New Orleans Saints
Jonathan Taylor, RB, Indianapolis Colts
Nick Foles, QB, Chicago Bears
Tua Tagovailoa, QB, Miami Dolphins
Note: All times are ET and games are on Sunday, Nov. 29 unless otherwise noted.
Julio Jones (hamstring), WR, Atlanta Falcons vs. Las Vegas Raiders, 1 p.m.
Jones left last week's game with a hamstring injury and wasn't able to put in a full practice this week. While it's not surprising it also puts his Week 12 status in doubt. The matchup against the Raiders is a good one and fantasy owners should start him as a WR1 if he's active, even with the hamstring and risk of him re-injuring it during the game.
Philip Rivers (toe), QB, Indianapolis Colts vs. Tennessee Titans, 1 p.m.
Even though Rivers seemed to have a toe injury in Week 11, he played through it, which seems to indicate he will be out there on Sunday. Rivers faces the Titans, which is a good matchup. When these two teams faced each other two weeks ago, Rivers had 308 yards, a touchdown and no interceptions. He should put up similar numbers in Week 12.
Giovani Bernard (concussion), RB, Cincinnati Bengals vs. New York Giants 1 p.m.
Bernard played in Week 11, but then popped up on the injury report with a concussion on Wednesday. As of Friday, it seemed that he was able to practice in full and just needed to formally clear the league's concussion protocol to play on Sunday. While it seems likely that he will be active, the team is without Joe Burrow and Bernard hasn't exactly been stellar with Joe Mixon out. Bernard is an RB3 if active.
Mark Andrews (thigh), TE, Baltimore Ravens at Pittsburgh Steelers, 8 p.m. (Tues.)
The Ravens haven't been able to actually practice because of their widespread COVID-19 issues, so fantasy owners shouldn't read into this injury report. Andrews will play if the game is played (currently a big if). However, Robert Griffin III will be the one throwing to him, which caps Andrews' already-limited upside.
Kalen Ballage (ankle), RB, Los Angeles Chargers at Buffalo Bills, 1 p.m.
Ballage played in Week 11, so it seems that he will be active in Week 12. However, Austin Ekeler was activated from injured reserve earlier this week, but it's not clear if he will play on Sunday. If Ekeler is active, Ballage's fantasy value will take a hit. However, if Ekeler sits out this game, Ballage would be an RB2. He's been involved in the passing game and has a higher value in PPR formats.
Jerry Jeudy (ankle), WR, Denver Broncos vs. New Orleans Saints 4:05 p.m.
The ankle injury isn't new, so fantasy owners shouldn't be concerned with him being active. What they should be concerned about is the fact that none of the three quarterbacks (Drew Lock, Jeff Driskel, Brett Rypien) on the Broncos' roster (or practice squad member Blake Bortles) are eligible to play on Sunday because of COVID-19. Either running back Royce Freeman or practice squad wide receiver Kendall Hinton will be throwing the ball to Jeudy. If you need an excuse to bench Jeudy, this is it.
Marquez Valdes-Scantling (Achilles), WR, Green Bay Packers vs. Chicago Bears, 8:20 p.m.
MVS has been a decent pass catcher for the Packers in the past few weeks, but he suffered an injury in practice on Thursday. Typically late-week additions to the injury report are never good, so MVS' status could be in doubt for Sunday night. Because this is the night game, fantasy owners should be looking to make other plans. Allen Lazard will likely have more targets if MVS is out and may be available in your league.
Hayden Hurst (ankle), TE, Atlanta Falcons vs. Las Vegas Raiders, 1 p.m.
Hurst missed practice on Wednesday, but fantasy owners will know early if he is active for Week 12. Hurst does have three touchdowns on the season, but he gave fantasy owners a goose egg in Week 11. The matchup against the Raiders is a good one, but he's just a TE2 this week, if active.
Jakeem Grant (hamstring), WR, Miami Dolphins at New York Jets, 1 p.m.
Grant suffered the hamstring injury in practice on Thursday, which never is good for playing on Sunday. The severity will determine Grant's status. However, in most fantasy formats, he was a WR3 at best in the first place, with two receptions for 12 yards in Week 11. The matchup is good, but don't expect more than WR3 production if Grant is active.
Tyler Higbee (elbow), TE, Los Angeles Rams vs. San Francisco 49ers, 4:05 p.m.
It's hard to trust Higbee regardless of the injury, but it should be noted that he missed practice on both Wednesday and Thursday this week. The team didn't practice on Friday (because of COVID-19). It looks like Higbee will come down to being a game-time decision for Week 12, which means fantasy owners may need to make other plans as the Rams play in the late afternoon window. If possible, grab Gerald Everett and start him, as his targets would increase if Higbee is out.
N'Keal Harry (shoulder), WR, New England Patriots vs. Arizona Cardinals, 1 p.m.
After doing next to nothing and dealing with injuries all season, Harry had eight targets in Week 11. It seems likely that he will play in Week 12 as he was just limited in Friday's practice, but his track record should be enough for fantasy owners to keep him on the bench.
Gardner Minshew (thumb), QB, Jacksonville Jaguars vs. Cleveland Browns, 1 p.m.
Minshew is listed as questionable, but the team has said that Mike Glennon will be the starter. It seems that the Jags may have Minshew available in an emergency situation (although it seems that is what Jake Luton is there for as well). Don't plan on starting Minshew in Week 12, but he will likely return in Week 13.
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.
(Top photo courtesy of colts.com)