The injury report for Week 16 is a short one, and most of the players that fantasy owners are counting on are either not on the injury report or have been added to injured reserve.
For running backs, note that Josh Jacobs has been ruled out, as has Dalvin Cook for Monday night, which is not surprising. In the case of Jacobs, DeAndre Washington automatically becomes an RB2 and Jalen Richard is a low-end flex play in PPR formats. As for Cook, Minnesota's backfield situation can best be described as "unsettled" (see below). As always, check the inactive reports before game time.
Note: All times are ET and all games are on Sunday, Dec. 22 unless otherwise noted.
Derrick Henry (hamstring), RB, Tennessee Titans vs. New Orleans Saints, 1 p.m.
Henry wasn't listed on the final injury report for the Titans that came out Friday afternoon. However, on Saturday afternoon news broke that he was downgraded to Questionable. It's also worrisome that the Titans promoted a running back from their practice squad. It's pretty much the worst news that fantasy owners relying on Henry in their fantasy championships could get. The good news is that the Titans are playing in the early slate of games and fantasy owners will know early if their RB1 is out. If he is active, trust him and hope that he won't be used as a decoy or in a backup or limited role.
DJ Chark Jr. (ankle), WR, Jacksonville Jaguars at Atlanta Falcons, 1 p.m.
After missing Week 15, Chark returned to limited practice this week, putting him on track to play in Week 16. He has a great matchup against the Falcons. The team expects to have him, so fantasy owners should expect to insert him back into their lineups. While it is possible he aggravates the ankle injury mid-game, he still should be a WR2 in Week 16.
Noah Fant (shoulder), TE, Denver Broncos vs. Detroit Lions, 4:05 p.m.
Fant injured his shoulder in Week 15, but he was able to return to the game and put in limited practices this week. He is officially listed as Questionable, but all signs point to him playing, although he certainly is at risk for in-game injury. Even with Drew Lock at quarterback, Fant has been a TE1. He can somewhat safely be penciled into Week 16 lineups but just make sure you have a Plan B since he doesn't play until the late-afternoon window.
Curtis Samuel (knee), WR, Carolina Panthers at Indianapolis Colt, 1 p.m
If you're looking for a reason to sit Samuel, this is it. He's been hit-or-miss all season and if he doesn't score a touchdown, he's not worth of starting in most fantasy formats. Add in a knee injury that popped up in practice at some point this week and caused him to miss practice entirely on Friday, and he should be on fantasy benches, even if active.
Christian Kirk (ankle), WR, Arizona Cardinals at Seahawks, 4:25 p.m.
This is not a new injury for Kirk, but it is one that is bothering him. Kirk hasn't missed any game time, but he has missed practice. He did put in limited practice this week, and even though he's considered a game-time decision, fantasy owners can likely assume he will play. It's going to be tough to trust him in a tough matchup and banged up, but he should be active.
Robby Anderson (illness), WR, New York Jets vs. Pittsburgh Steelers, 1 p.m.
Most of the time players do not miss games due to illness (although it has happened with this team, right Le'Veon Bell?). Fantasy owners should expect to have Anderson, although the matchup is tough. In an equally tough matchup in Week 15, Anderson had four receptions for 66 yards. Expect a similar stat line in Week 16.
Bo Scarbrough (ribs), RB, Detroit Lions at Denver Broncos, 4:05 p.m.
Scarbrough missed Week 15 with the ribs injury and he is Questionable for Sunday's game. It doesn't really matter though, as fantasy owners shouldn't plan on using him. Kerryon Johnson is eligible to return from IR and all signs point to him playing. He won’t have an every-down role, but what that does is make all Lions running backs poor fantasy options this week.
Alexander Mattison (ankle), RB, Minnesota Vikings vs. Green Bay Packers, 8:15 (Mon.)
After missing Week 15, Mattison returned to practice on a limited basis on Saturday. It doesn't mean he'll be cleared in time to play on Monday night, but because of the timing, there's a chance. What it really does is muddy the waters somewhat when it comes to labeling Mike Boone as the must-start option in place of Dalvin Cook, who is not expected to play. This put fantasy owners in a lurch, which is not a good place to be if you're fighting for a championship. As it relates to Mattison, even if he's able to play it's probably not worth the risk to use him in your lineup.
Jordan Howard (shoulder), RB, Philadelphia Eagles vs. Dallas Cowboys, 4:25 p.m.
Howard hasn't played since Week 9 and it doesn't look like he'll return on Sunday either. It's unclear at this point while he is still on fantasy rosters. He hasn't been cleared for contact, which probably means he's not suiting up on Sunday, despite the Questionable tag. He can be safely dropped.
Nelson Agholor (knee), WR, Philadelphia Eagles vs. Dallas Cowboys, 4:25 p.m.
It's unclear why Agholor is listed as questionable rather than ruled out. He's missed the past two weeks with the knee injury and he hasn't practiced. There were reports of him being shut down for the rest of the season; none of this sounds like he's playing. He's droppable in redraft formats.
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.