It's Week 2 and fantasy owners likely are already affected by injuries. Many players were injured in Week 1 (or earlier) and fantasy owners will need to adjust their lineups accordingly. Some big names are out this week, especially among the wide receivers.
Often when a running back is out, there is a clear handcuff. However, when it comes to wide receivers, it is often hard to find out who will be the next man up. In some cases, the team gives an indication; in others, it's anyone’s guess. Fantasy owners should look at depth charts and the previous week's targets in order to get an idea of who might be the beneficiary of a player being out. If a player is questionable, be sure to check the inactive report before game time to know whether to start that player or not.
A.J. Brown, WR, Tennessee Titans
Jamison Crowder, WR, New York Jets
Chris Godwin, WR, Tampa Bay Buccaneers
Kenny Golladay, WR, Detroit Lions
Alshon Jeffrey, WR, Philadelphia Eagles
Michael Thomas, WR, New Orleans Saints
Note: All times are ET and all games are on Sunday, Sept. 20 unless otherwise noted.
Amari Cooper (foot), WR, Dallas Cowboys vs. Atlanta Falcons, 1 p.m.
Fantasy owners relying on Cooper can breathe easy — it seems like he should play and he has a great matchup. He was able to practice and he's calling the foot injury a bruise. In Week 1, Cooper had 14 targets. He caught 10 of those for 81 yards. He's clearly the No. 1 receiver in Dallas and is a WR1 for Week 2.
Julio Jones (hamstring), WR, Atlanta Falcons at Dallas Cowboys, 1 p.m.
No one at the Falcons organization seems to be concerned with Jones' hamstring, so fantasy owners should also not be concerned. Jones had nine receptions for 157 yards on 14 targets in Week 1. He's a WR1 against the Cowboys in a game that certainly has the potential to be high scoring.
Courtland Sutton (shoulder), WR, Denver Broncos at Pittsburgh Steelers, 1 p.m.
Last week, Sutton was a game-time decision and was ultimately ruled out. He's a game-time decision again for Week 2, but at least this week, the Broncos play in the early slate of games. Sutton may be hard to trust in his first game back, but fantasy owners can treat him as a WR3 if active. The Broncos may also have rookie KJ Hamler this week.
DeVante Parker (hamstring), WR, Miami Dolphins vs. Buffalo Bills, 1 p.m.
Parker came into Week 1 with a hamstring injury and he tweaked it during the game. He had four receptions for 47 yards, but this isn't an indicator of what the receiver can do. Parker was able to practice all week, but the team obviously wants him healthy. He's listed as a game-time decision, but he will likely play. The problem is if the team puts him on a snap count or pulls him if the game becomes too lopsided. Fantasy owners should start him with risk — but keep him on the bench if you have any other decent options.
Brandin Cooks (quad), WR, Houston Texans vs. Baltimore Ravens, 4:25 p.m.
Cooks has been playing through his quad injury and will continue to play through it this week. However, he has a tough matchup against the Ravens, and even though the Texans will likely be throwing the ball, it's going to be hard to trust him. In Week 1, he had two receptions for 20 yards on five targets. Fantasy owners should expect more of the same in Week 2.
Julian Edelman (knee) and N'Keal Harry (shoulder), WRs, New England Patriots at Seattle Seahawks, 8:20 p.m.
Both receivers will likely be active in Week 2 as these are not new injuries. Both players were on the injury report ahead of Week 1 and both played. Harry caught five receptions for 39 yards on six targets and Edelman caught five receptions for 57 yards on seven targets. It's going to be hard to trust either receiver. Edelman is nothing more than a WR3, Harry a WR4 in their matchup against Seattle.
Golden Tate (hamstring), WR, New York Giants at Chicago Bears, 1 p.m.
Tate missed Week 1 with the hamstring injury, but after practicing this week, seems ready to play in Week 2. It's not clear if the team will ease him into game action or not, but either way, fantasy owners shouldn't be too excited about starting him. Sterling Shephard and Darius Slayton are the two receivers to start in fantasy for the Giants.
Michael Pittman Jr. (toe) and Zach Pascal (ankle), WRs, Indianapolis Colts vs. Minnesota Vikings, 1 p.m.
Pittman injured his toe in practice on Thursday and did not practice on Friday. The team is calling him a game-time decision, which is tough for fantasy owners. While they will know early, the best option is to leave Pittman on the bench. Pascal was able to practice on Friday and also isn't a good fantasy option unless you are in a deeper league. He may come in for a few snaps, but Pascal is really one of those dart-throw, desperation options.
Henry Ruggs (knee), WR, Las Vegas Raiders vs. New Orleans Saints, 8:15 p.m. (Mon.)
After not practicing Thursday or Friday, fantasy owners were starting to get a little concerned about Ruggs. However, he did manage to practice on Saturday (the equivalent of a Friday practice for those playing on Sunday), which does help. It doesn't seem that the knee injury is structural; perhaps a bone bruise or contusion of some kind. However, Ruggs will likely be a game-time decision, which is tough for fantasy owners because he doesn't play until Monday. The safest bet is to find another option as Ruggs only had three receptions for 55 yards in Week 1. If you also have Bryan Edwards, you can wait to make the decision, but waiting for Ruggs may just be disappointing.
— Rankings by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.