Fantasy owners need to be prepared for anything, including games moving around and injuries. It is a lot to follow, and one of the downsides of having two games on Monday and one on Tuesday is that a final injury report is not given and fantasy owners aren't going to know if their players are active until after the Sunday slate of games.
In some leagues, add/drops are allowed if the player hasn't played (you can pick up Cole Beasley, for example, on Monday or Tuesday and drop a player on your bench if you need someone to fill in). Take a look at your league's rules and plan your lineup accordingly. As always, be sure to check the inactive report before game time. And remember, Detroit and Green Bay are on bye.
Teams on bye: Detroit, Green Bay
Bryan Edwards, WR, Las Vegas Raiders
KJ Hamler, WR, Denver Broncos
DeSean Jackson, WR, Philadelphia Eagles
Alshon Jeffery, WR, Philadelphia Eagles
Breshad Perriman, WR, New York Jets
Note: All times are ET and all games are on Sunday, Oct. 11 unless otherwise noted.
Michael Thomas (ankle), WR, New Orleans Saints vs. Los Angeles Chargers, 8:15 p.m. (Mon.)
Thomas was able to get in limited practices this week, so he should be on track to play Monday night. He hasn't played since Week 1. This is a situation where it gets tricky. He's a WR1 if active, no questions asked. However, if he's not active, fantasy owners aren't going to know until Monday night. All signs point to him playing — but be sure you have a backup player (or can acquire one from the waiver wire) just in case.
Julio Jones (hamstring), WR, Atlanta Falcons vs. Carolina Panthers, 1 p.m.
It's unclear why Jones got a Questionable designation instead of Doubtful. He re-aggravated his hamstring in Week 4 and didn't practice all week. He's not going to play in Week 5. If for some reason he's active, fantasy owners should keep him on the bench as it's likely a case of "in an emergency only."
A.J. Brown (knee), WR, Tennessee Titans vs. Buffalo Bills, 7 p.m. (Tues.)
Sunday a.m. update: The Titans/Bills game appears to be in jeopardy following another positive test in Tennessee. It is very likely that Brown (and the Titans will not play this week. If your league does not offer the opportunity to list a substitute player, remove Brown from your line-up before Sunday kick-off. It's just too risky.)
Brown hasn't played since Week 1, where he suffered a bruise to the knee which has kept him sidelined for two games and a surprise bye week. All reports have said that he is ready to return in Week 5. Corey Davis and Adam Humphries are both on the Reserve/COVID-19 list and not expected to be cleared in time to play. This means that Brown becomes a WR1 for fantasy owners. Put him in your starting lineup, but be sure to watch to see any signs that he may not play. The Tuesday game really makes things dicey for fantasy owners.
Deebo Samuel (illness), WR, San Francisco 49ers vs. Miami Dolphins, 4:05 p.m.
In past years, an "illness" rarely kept a player from playing. However, past years are NOT 2020. That being said, Samuel has not tested positive for COVID-19, and he should be fine to play. Players are allowed to get sick with illnesses other than COVID-19 and play, and this is likely the case with Samuel. Fantasy owners should be relieved that he is not on the injury report with his foot injury. Samuel is a WR2 this week.
Marquise Brown (knee), WR, Baltimore Ravens vs. Cincinnati Bengals, 1 p.m.
It's usually unnerving when a player pops up on the injury report, but it seems that Brown is good to go. He was limited at practice on Wednesday but was able to put in a full practice on Friday. Fantasy owners should put Brown in their lineup with confidence. He's a borderline WR1 for Week 5.
Henry Ruggs (knee/hamstring), WR, Las Vegas Raiders at Kansas City Chiefs, 1 p.m.
Ruggs was able to practice in full on Thursday and Friday so he should be ready to go for Week 5. He missed Weeks 3 and 4, but he is expected to return against a tough Chiefs defense. Ruggs will assume the No. 1 wide receiver role for the Raiders, but he will lose targets to Darren Waller and Hunter Renfrow. The Chiefs will likely attempt to take Waller out of the game, which bodes well for Ruggs. He's a WR3 this week.
John Brown (calf), WR, Buffalo Bills at Tennessee Titans, 7 p.m. (Tues.)
Sunday a.m. update: The Bills/Titans game is in jeopardy following another positive case in Tennessee. In order to be safe, remove John Brown from your line-up and replace him with another WR3 before Sunday's games begin.
Brown was removed from the injury report ahead of Week 4's game, and he finished with four receptions for 42 yards. He did get in limited practices this week and should be fine to play on Tuesday night. Fantasy owners aren't getting the production that they had hoped for (or saw last season) from Brown, but he should be active as a WR3 for fantasy this week.
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.