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NFL DFS: Best DraftKings and FanDuel Predictions and Picks for Week 6

NFL DFS: Best DraftKings and FanDuel Predictions and Picks for Week 6

NFL DFS: Best DraftKings and FanDuel Predictions and Picks for Week 6

As of now, all games are scheduled to play, which makes me excited about my Week 6 daily fantasy football (DFS) picks. Of course, COVID-19 is just one piece to the puzzle, we still have to worry about regular old-fashioned injuries. But I am assuming you already know that Dalvin Cook is out this week, making Alexander Mattison both a cheap and chalky play.

In fact, most of the players in the Vikings/Falcons game are the chalk play but the only one I will be featuring here is one of the far less chalky options. If you are playing only 50/50s and other cash games, I would load up on that game for the most part.

However, if you're looking for other options, especially for GPPs, check out my week 6 DFS picks below.

Week 6 Positional Rankings: QB I RB I WR I TE I DST I K I Flex

Teams on bye: Las Vegas, Los Angeles Chargers, New Orleans, Seattle

Safe Quarterback Week 6 Pick

Matthew Stafford, Lions at Jaguars (DK $6300, FD $7300)

The Detroit/Jacksonville game is one of the higher over/unders this week so there should be a high volume of scoring on both sides. And with Jacksonville giving up the seventh-most fantasy points to QBs, this is looking like a great matchup for Stafford. In addition to a strong matchup, Stafford will be well rested coming in off the bye. However, he might not have wanted the break. His touchdown rate has been steadily rising each week. He's now up to eight touchdowns through four games and should easily match his two-touchdown-a-game average and might even double that in Jacksonville this weekend.

High Risk/Reward Quarterback Week 6 Pick

Gardner Minshew, Jaguars vs. Lions (DraftKings $6400, FanDuel $7200)

I really haven't highlighted Minshew much this year and I need to rectify that. Let's start with something many heard about, but still not enough did. And that was his Bud Light campaign. On the chance you missed it, here it is again.

There are so many great things here. For one, the fact that Minshew seems to care, or at least mockingly care about his fantasy status automatically elevates him above nearly every other quarterback. So rather than focus on all of the other great things about the tweet above, let's just focus on Minshew's chance for success this weekend.

The Lions are a popular pick to score quite a bit this weekend. But if the Lions are going to be scoring a lot of points, might it be possible that the Jaguars will try and keep up? The answer is obviously yes, especially given that the Lions are in the top 10 (ninth) in terms of most touchdown passes allowed. Minshew has thrown two or more touchdowns in four of five games this year. In addition to his TD prowess, Minshew is averaging a very respectable 288 passing yards per game. Minshew can sometimes wilt under tough opposition, but the Lions are one of the 10 worst teams in preventing fantasy points to the quarterback position.

Now add the two additional layers that Minshew is likely to be low owned and also is very affordable. When it comes to the Week 6 GPP DFS values, Gardner you're one of the best around.

Safe Running Back Week 6 Pick

Myles Gaskin, Dolphins vs. Jets (DK $5400, FD $5700)

Gaskin had his best game yet with nearly 100 combined yards and a touchdown against the 49ers. He now gets to face the Jets at home this week. The Jets' run defense is miles (see what I did there?) behind the 49ers. Let's move on before I make any more bad puns, shall we?

High Risk/Reward Running Back Week 6 Pick

La'Mical Perine, Jets at Dolphins (DK $4000, FD $4600)

Perine offers us a nice opportunity at the absolute minimum and second-lowest salary on the sites respectively. Obviously, when choosing players priced that low, we should keep our expectations in check. But I absolutely love Perine's upside this week. And while I'm not a Gator fan, seeing his college highlights gets me juiced for his possibilities this weekend:

I'm making the presumption that you heard Le'Veon Bell was released (and has since signed with Kansas City), but that happened after the sites assigned salary, leaving Perine at a rock-bottom cost. But the Dolphins are a pretty ideal matchup. They have allowed a TD less than every 16 RB touches. In addition to enabling RBs to find the end zone, Miami has allowed 4.97 yards per carry and 6.81 yards per target.

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We know what we're getting with Frank Gore as he continues to be the nemesis of Father Time. And unfortunately, Perine will still be playing under Adam Gase. However, that might not be the case for much longer. And whoever the Jets head coach is, even if it's still Gase, he is going to need to determine if Perine is the long-term answer. Perine was not given a whole lot of opportunities even when was Bell was injured. But now that he is officially gone, I do expect the Jets to increase his workload. And at such minimal cost, I'm willing to take a chance it's this weekend.

Safe Wide Receiver Week 6 Pick

Davante Adams, Packers at Buccaneers (DK $8000, FD $9000)

I am grabbing Adams more for his floor this week than his ceiling. Because the truth is the Bucs' secondary has been pretty good. However, it hasn't been that good. They have given up the sixth-most fantasy points to quarterbacks. But they are also tied with seven other teams for the sixth-fewest TD passes. And they are 18th in passing yards allowed. It's not a soft matchup, but it's not one to run away from either.

Furthermore, the Bucs recently lost both LB Jake Cichy and DL Vita Vea to injured reserve. Tampa Bay can probably survive without Cichy this week, but the loss of Vea is huge. Vea was ranked the third-best interior lineman coming into last week's games. The loss might be going under the radar, but it shouldn't. One of the reasons that Rodgers "You Ain't Ready For Love" tour is going strong is because he has not been pressured very much. He's been sacked just three times this season and is one of the best quarterbacks in the game when he can stay in the pocket. I think he will hit a bump against a team that can pressure Rodgers. But that's not the Buccaneers.

Rodgers and his pass catchers should see big numbers. And that starts with Adams. His cumulative stats are nothing impressive as he has not played the last three weeks due to a bye and injuries. But Adams still averaged double-digit targets to start the season and should see close to that number this week as well.

High Risk/Reward Receiver Week 6 Pick

Damiere Byrd, Patriots vs. Broncos (DK $3500, FD $5100)

I am definitely going to go with a lot of pricey options this week but partly because I'm going with some very cheap options and that includes Byrd as my WR3. It's definitely one of the more aggressive picks featured this week, but I love his upside at this low price. The Broncos are giving up the fourth-most fantasy points to WRs and I like him for a lot of the same reasons I like Darnell Mooney, whom I've discussed in a previous article.

Like Mooney, Byrd has very quietly become the WR2 for his team. Unlike Mooney though, it looks like Bryd will have Comeback Player of the Year candidate (unless Alex Smith wins in a landslide) Cam Newton tossing him passes. Byrd saw double-digit targets his last game and if that continues this low price is not going to last long.

Safe Tight End Week 6 Pick

Mark Andrews, Ravens at Eagles (DK $6500, FD $7600)

We can argue if he's worth the cost, but with both George Kittle and Travis Kelce playing the primetime games, this is the obvious pick to produce on the main slate. There is no debate or need to discuss further.

High Risk/Reward Tight End Week 6 Pick

Irv Smith Jr., Vikings vs. Falcons (DK $2500, FD $4300)

Last time I went with Smith, it didn't go well. But he is even cheaper now. And when you go this cheap, even a couple of catches for 20 yards earns you a profit. Smith is not even priced within the top 25 TEs this week! Yet he could easily be a top-20 play at the position.

Now in his second season, Smith is starting to flash some of the potential that many believe will lead to a big year next year. He might arrive earlier than expected. If he continues to run passing routes on more than 70 percent of the Vikings' pass plays, like he did on Sunday night against Seattle, he'll be a fantasy asset sooner rather than later.

Add in the fact that no defense playing this week is giving up more fantasy points to TEs than Atlanta and this is an incredible buying opportunity. It is the absolute definition of a GPP value play.

Safe Defense/Special Teams (DST) Week 6 Pick

Patriots vs. Broncos (DK $3500, FD $4800)

The Patriots' defensive rankings have ping-ponged all over the place this year. But let's not over-analyze this. They are just one of five teams in the NFL averaging two or more takeaways a game. They are giving up 23 points per game. Their opponent this weekend, the Broncos, have rank 28th in scoring offense (20.5 ppg). Drew Lock might play for the Broncos this weekend, he might not. It doesn't change things too much. The Patriots D might not be an elite play this weekend, but they should definitely finish in the top half in Week 6.

High Risk/Reward Defense/Special Teams (DST) Week 6 Pick

Panthers vs. Bears (DK $2900, FD $3700)

The Panthers on the other hand are far more interesting. Above I mentioned that the Broncos are 28th in the league in scoring. Guess who is 27th? Chicago, otherwise known as Carolina's opponent on Sunday. The Panthers are actually an interesting aberration. They are getting absolutely steamrolled on the ground and have given up the most rushing TDs. Yet they are one of the top pass defenses in the leagues. They've given up the third-fewest touchdown passes. But it's not because of their pass rush, which is tied with Jacksonville for last in sacks per game. Carolina also has one of the lowest interception rates in the league. So something has to give. And given the accuracy issues that Nick Foles is having, plus the Bears' offensive line is regarded as below average nearly anywhere you look, the Panthers DST could be a seemingly under-the-radar move that pays off quite well.

— Written by Mark Strausberg, a member of the Athlon Network Contributor, who despite his youthful exuberance and good looks has been playing fantasy sports before Wildcats or Hoosiers even made it to VHS. Got a fantasy sports question or thought? Hit him up on Twitter @MarkStrausberg.

(Top photo courtesy of