Even though San Francisco's Blaine Gabbert did look capable against the Seattle Seahawks in Week 11, there's no disputing that the Arizona Cardinals will be a tough test for him and a depleted 49ers offense. The Cardinals have been a solid fantasy DST all season, and are the No. 1 option for Week 12.
The Kansas City Chiefs, since their Week 9 bye, have put up 20 points in standard DST scoring over the past two weeks. Justin Houston and his running mates are a solid option as well. Typical top defenses, Seattle and Denver, have tougher matchups this week, and fall a bit down the rankings.
Here are the Week 12 DST rankings:
Fantasy Football Rankings powered by FantasyPros
— Written by Sarah Lewis, who is part of the Athlon Contributor network and lives, eats, and breathes fantasy football. She also writes for SoCalledFantasyExperts.com among other sites. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.