When looking at a defense/special teams to round out your fantasy football lineup, the biggest key is pick a defense from the team that should win the game. Typically home teams fare better than the visiting teams, but that's not always the case.
For example, Carolina is basically matchup-proof, which is why Luke Kuechly and the Panthers come in at No. 2 this week even though they are playing in Denver, while the visiting Rams are appealing because of their opponent (49ers).
For Week 1, the DST rankings are based on last year's performance and how they have looked in the preseason. It's hard to tell what will happen in a new season, but here are the Week 1 DST rankings:
— Written by Sarah Lewis, who is part of the Athlon Contributor network and lives, eats, and breathes fantasy football. She also writes for SoCalledFantasyExperts.com among other sites. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.