As we head into the first football Sunday of the year, we need to look at players that are battling injuries already. Most of these players had injuries that forced them to miss some (or all) of the preseason, and they were hoping to play in Week 1. LeSean McCoy is the biggest name on this list, and the good news is that he should play in Week 1. Other running backs and some tight ends are facing Questionable tags, meaning their playing status is 50/50. Be sure to check your fantasy lineups to ensure that everyone that is starting for you is playing this weekend. Here are the latest updates to running backs and tight ends. Don't forget to check on the wide receiver injury update as well.
LeSean McCoy, RB, Buffalo Bills vs. Indianapolis Colts
Probable - Hamstring
McCoy pulled his hamstring in the middle of August and has said all along that he would be ready for Week 1. He did practice in full Wednesday and Thursday this past week, so he will play in Week 1. However, he has admitted that he is not 100 percent. As long as he doesn't suffer a setback in the game, he will be a solid RB1.
C.J. Spiller, RB, New Orleans Saints at Arizona Cardinals
Out - Knee
Spiller has been ruled Out for Week 1 as he recovers from his knee scope. It is possible he will be ready for Week 2, but fantasy owners will have to watch the practice reports this coming week to get a feel for his status. In the meantime, Mark Ingram will be the primary running back and Khiry Robinson will likely handle some of the passing downs. Ingram is a RB1, and Robinson is worth a flyer as a RB3 in PPR leagues.
Devonta Freeman, RB, Atlanta Falcons vs. Philadelphia Eagles (Mon.)
Questionable - Hamstring
The Falcons play on Monday night, so lineup decisions are going to have to be made before any word is made officially on Freeman's status. He's been battling a hamstring injury for over a month now. Freeman did not play in the last preseason game, although had it been a regular season game, he likely would have played. Reports from practice this week revealed that the hamstring still isn't 100 percent. Freeman will likely play Monday night, but look for Tevin Coleman to have the majority of the carries. Between the late game and the possibility of a setback, avoid Freeman for fantasy.
Tre Mason, RB, St. Louis Rams vs. Seattle Seahawks
Questionable - Hamstring
After pulling his hamstring in the third preseason game, Mason has not been practicing. Mason had a hamstring injury earlier in the summer and this was an aggravation that he still has not recovered from. With Todd Gurley already ruled out, the third running back on the roster is Benny Cunningham. The matchup against the Seahawks is going to be a tough one regardless of who plays, so it may be in the best interest of the Rams to hold Mason out until he fully heals. They are going to slowly ease Gurley in, but they also don't need to rush an injured Mason out on the field.
Duke Johnson, RB, Cleveland Browns at New York Jets
Probable - Hamstring/Concussion
While Johnson may end up being the starting running back for Cleveland, he's likely going to be eased into game action this weekend. He's been cleared to play, but the role he will have is still up in the air. Johnson is more of a pass catcher than Isaiah Crowell, so he should be in for passing downs. Unfortunately for the Browns, they are playing the Jets in Week 1, who had a stout run defense in 2014. The upside of Johnson is that he and Crowell are the two healthy running backs on the Browns roster. However, that's not a reason to start him unless you have to.
Zach Ertz, TE, Philadelphia Eagles at Atlanta Falcons (Mon.)
Questionable - Groin
As a reminder, the Eagles play on Monday night, so hopefully you have better options at tight end. While Ertz has been a trendy sleeper in the past, this preseason has been marred by groin surgery and the recovery from surgery. He will likely be a game-time decision for Monday's game, so don’t hold out for him.
Ladarius Green, TE, San Diego Chargers vs. Detroit Lions
Questionable - Concussion
With Antonio Gates already suspended for the first four games, it was Green's chance to earn a role in the offense. However, Green suffered a concussion in practice this week and is Questionable for Week 1. He did practice on Friday, but has not cleared through the concussion protocol. If he can be cleared, he will play and is a TE2. However, the Chargers play in the late games on Sunday as well, so if you have another tight end to plug in, use him. Don't look for the third tight end on the Chargers depth chart to fill in your roster. Find another option.
— Written by Sarah Lewis, who is part of the Athlon Contributor network and lives, eats, and breathes fantasy football. She also writes for SoCalledFantasyExperts.com among other sites. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.