Following Week 1, fantasy owners have to be aware of a number of injuries. Three fantasy-relevant players are now on injured reserve: Derrius Guice, Nick Foles, and Devin Funchess. Other players who have already been ruled out for Week 2 include Tyreek Hill, Hunter Henry, Sterling Shepard, Sam Darnold, Tevin Coleman, and Jordan Reed. Fantasy owners should look to the next man up in each of those situations if possible. Many backups (Matt Breida, Vernon Davis) are already owned, but if they are not, they should be.
As always, be sure to check the final injury report that is released on about an hour and a half before the games.
Note: All times are ET and all games are on Sunday, Sept. 15 unless otherwise noted.
Le'Veon Bell (shoulder), RB, New York Jets vs. Cleveland Browns (Mon.)
Based on the practice schedule, fantasy owners should plan on having Bell in their lineups on Monday night. He had an MRI and the results were good enough that he should play in Week 2. Sam Darnold is out, so Bell should be relied upon more with Trevor Siemian at quarterback. Plan on starting him as an RB1.
Joe Mixon (ankle), RB, Cincinnati Bengals vs. San Francisco 49ers, 1 p.m.
Mixon has an ankle injury, but he was able to return to practice on Friday after missing Wednesday and Thursday. It seems like he's going to try to play in Week 1, but fantasy owners should be sure to check the inactive report. The problem for fantasy owners is going to be if he is limited or suffers an in-game injury. Mixon should be treated as an RB2 for Week 1 if active. If he is inactive, Giovani Bernard would be an RB2.
Mark Ingram (shoulder), RB, Baltimore Ravens vs. Arizona Cardinals, 1 p.m.
Ingram has missed some practice time (limited on Wednesday) and earned the questionable tag, but fantasy owners shouldn't be worried about his status for Week 2. Ingram will play and should be considered an RB2. He had 107 yards and two touchdowns in Week 1. He'll still share carries with Gus Edwards, but he's the starting running back.
Marquise Brown (hip), WR, Baltimore Ravens vs. Arizona Cardinals, 1 p.m.
Even with the hip injury and the missed Friday practice, the word from the team is that he will be active in Week 2. Prior to Week 1, he also missed the Friday practice and played (although his snap count was low). He managed to do well with a limited snap count: catching four balls on five targets for 147 yards and two touchdowns. The team will likely slowly increase his role, and while he may not get two touchdowns again this week, it is a great match-up for him. Start him as a WR3.
Mike Williams (knee), WR, Los Angeles Chargers at Detroit Lions, 1 p.m.
Williams left Week 1 with a knee injury and missed practice time this week. He's truly questionable for Week 2, so fantasy owners should make sure they check the inactive report. However, the safest bet would be to keep Williams on the bench this week. Williams did practice on Friday but the team was concerned about the knee earlier in the week. If he is active, he may be limited. Bench him if possible.
Cody Latimer (calf), WR, New York Giants vs. Buffalo Bills, 1 p.m.
Sterling Shepard is already ruled out; Golden Tate is still suspended. The Giants are really running out of people to throw the ball to. Latimer would be the next man up and fantasy owners should consider him for Week 2, if he plays. Latimer missed Thursday's practice and is questionable for Week 2. Fantasy owners can gamble on Latimer if active, but know that it is simply a gamble.
Mark Andrews (foot), TE, Baltimore Ravens vs. Arizona Cardinals, 1 p.m.
The reports on Andrews are confusing — he practiced Wednesday and Thursday but missed Friday. However, no new injury seemed to be listed. Fantasy owners should plan on having Andrews in their lineup in Week 2 as a low TE1. The matchup against Arizona is an excellent one. In Week 1, Andrews had eight targets and he caught them all for 108 yards and a touchdown. He should be good to go in Week 2.
Trey Burton (groin), TE, Chicago Bears at Denver Broncos, 4:25 p.m.
Burton missed Week 1 with the groin injury, but was able to practice on Wednesday. This is usually a good sign for a player's availability for the upcoming week. Fantasy owners should be a little nervous, however, as the team has not committed to him playing. In addition, with the Bears playing in the late afternoon slate, this may be a tough one for fantasy owners to wait on. Burton is a TE2 if active as his usage may be lowered because of the time missed. The safest bet is to play another tight end if possible.
— Written by Sarah Lewis, who is part of the Athlon Contributor Network and lives, eats, and breathes fantasy football. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.