On Sunday night, San Francisco will look to become the first team to win at Seattle this season.
A betting preview of every game (against the spread) in Week 16.
Locks of the Week
Two divisional rivalry showdowns plus another two matchups of the haves and have nots look like good picks in a tough week to call.
49ers (-1) at Seahawks
Seattle is 6â0 at home this season; but New England had won 20 straight at home in December before last weekâs San Fran upset.
Bears (-6) at Cardinals
Ken Whisenhunt is probably on his way out anyway, might as go out with a Dennis Green-style rant after a Chicago loss.
Redskins (-6.5) at Eagles
RG3 is set to play against Philly, a team he went 14-of-15 with four TDs against during a 31â6 blowout win in Week 11.
Patriots (-14.5) at Jaguars
The Pats has won by 15 or more points in four of their seven road games â against the Titans (34â13), Bills (52â28), Rams (45â7) and Jets (49â19).
Saturday Night Fever
With no Thursday of Monday night games, the NFL schedule breaks out its first Saturday night prime time affair.
Falcons (-4.5) at Lions
Detroit has lost six straight, with three road games by five or more points and three home games by a combined nine points.
Straight Up Upset
This field goal spreads could come down to just that; but the game-winning kick might just come from the foot of an underdog.
Ravens (+3) vs. Giants
Baltimore has lost three straight contests, while New York has fallen in its last three road games â including a 34â0 whipping at Atlanta last week.
Bad Teams, Worse Opponents
The Ryan brothers have been up and down â mostly down â this year, but the Bolts and Aints have had even harder times.
Jets (-2.5) vs. Chargers
San Diego has gone 7â16 in games played in the Eastern Time Zone under Norv Turner.
Cowboys (-3) vs. Saints
New Orleans is 2â5 on the road, while Dallas has won five of its last six, including three of its last four at home.
Steer clear of these games unless you happen to be a degenerate or a hometown homer who has to have action on every game, all the time.
Buccaneers (-3) vs. Rams
St. Louis is 2â3â1 on the road, with wins over bottom feeders Arizona and Buffalo the past two weeks.
Steelers (-4) vs. Bengals
Cincinnati is riding a five-game losing streak against the AFC North rivals from Pittsburgh.
Dolphins (-4.5) vs. Bills
Buffalo beat Miami, 19â14, in Week 11 during a game that featured four FGs and a punt return TD.
Colts (-7) at Chiefs
Indy has only one win by eight or more points this season, on the road at Jacksonville.
Panthers (-9) vs. Raiders
Oakland is 0â4 in the Eastern Time Zone this year, but Carolina canât be trusted.
Texans (-9) vs. Vikings
Adrian Petersonâs quest to join the 2,000-yard club may hit a Watt wall in Houston.
Packers (-12.5) vs. Titans
Tennessee may need CJ2K to break another 90-plus-yard TD run to stay within a Lambeau Leap.
Broncos (-13) vs. Browns
Peyton Manning will pull off the win, but Cleveland is improved with a 3â1 record the last four weeks.