Week 2 of the 2021 NFL season kicks off with the New York Giants and Washington Football Team on "Thursday Night Football," one of six divisional matchups on the schedule. The AFC East and NFC South also will be engaged in divisional play in Week 2 including the Patriots seeing Jets rookie quarterback Zach Wilson for the first time. AFC contenders Kansas City and Baltimore will face off on "Sunday Night Football" while an NFC North matchup between Detroit and Green Bay wraps up things on "Monday Night Football."
We're here to keep you updated on the full NFL regular-season schedule, including start times and byes. Athlon Sports also has the full Thursday night, Sunday night, and Monday night slates if you are looking for a more specific breakdown.
Note: All times are ET and subject to change.
Thursday, Sept. 16
New York Giants at Washington, 8:20 p.m.
Sunday, Sept. 19
New Orleans at Carolina, 1 p.m.
Cincinnati at Chicago, 1 p.m.
Houston at Cleveland
Los Angeles Rams at Indianapolis, 1 p.m.
Denver at Jacksonville, 1 p.m.
Buffalo at Miami, 1 p.m.
New England at New York Jets, 1 p.m.
San Francisco at Philadelphia, 1 p.m.
Las Vegas at Pittsburgh, 1 p.m.
Minnesota at Arizona, 4:05 p.m.
Atlanta at Tampa Bay, 4:05 p.m.
Dallas at Los Angeles Chargers, 4:25 p.m.
Tennessee at Seattle, 4:25 p.m.
Kansas City at Baltimore, 8:20 p.m. (SNF)
Monday, Sept. 20
Detroit at Green Bay, 8:15 p.m.