Week 2 of the 2022 NFL season kicks off with a huge early-season AFC showdown between the Los Angeles Chargers and Kansas City on "Thursday Night Football." It's one of five divisional games on the slate, including Chicago and Green Bay on "Sunday Night Football." The week concludes with a "Monday Night Football" doubleheader featuring Tennessee at Buffalo and Minnesota at Philadelphia.
We're here to keep you updated on the full NFL regular-season schedule, including start times and byes. Athlon Sports also has the full Thursday night, Sunday night, and Monday night slates if you are looking for a more specific breakdown.
Note: All times are ET and subject to change.
Thursday, Sept. 15
Los Angeles Chargers at Kansas City, 8:20 p.m.
Sunday, Sept. 18
Miami at Baltimore, 1 p.m.
New York Jets at Cleveland, 1 p.m.
Washington at Detroit, 1 p.m.
Indianapolis at Jacksonville, 1 p.m.
Tampa Bay at New Orleans, 1 p.m.
Carolina at New York Giants, 1 p.m.
New England at Pittsburgh, 1 p.m.
Atlanta at Los Angeles Rams, 4:05 p.m.
Seattle at San Francisco, 4:05 p.m.
Cincinnati at Dallas, 4:25 p.m.
Houston at Denver, 4:25 p.m.
Arizona at Las Vegas, 4:25 p.m.
Chicago at Green Bay, 8:20 p.m. (SNF)
Monday, Sept. 19
Tennessee at Buffalo, 7:15 p.m.
Minnesota at Philadelphia, 8:30 p.m.