Week 5 of the 2021 NFL season gets going with an important NFC West battle between the Los Angeles Rams and Seattle Seahawks on "Thursday Night Football." Elsewhere on the schedule the Jet and Falcons will face off in London on Sunday as overseas play returns and the Dolphins and Buccaneers will face off for Sunshine State bragging rights. In prime time, it's a rematch of last season's AFC Championship Game between Buffalo and Kansas City on "Sunday Night Football" and Week 3 concludes with Indianapolis and Baltimore squaring off on "Monday Night Football."
We're here to keep you updated on the full NFL regular-season schedule, including start times and byes. Athlon Sports also has the full Thursday night, Sunday night, and Monday night slates if you are looking for a more specific breakdown.
Note: All times are ET and subject to change. Flex scheduling rules apply starting Week 5 and are in effect Weeks 5-17.
Thursday, Oct. 7
Los Angeles Rams at Seattle, 8:20 p.m.
Sunday, Oct. 10
New York Jets vs. Atlanta (London), 9:30 a.m.
Philadelphia at Carolina, 1 p.m.
Green Bay at Cincinnati, 1 p.m.
New England at Houston, 1 p.m.
Tennessee at Jacksonville, 1 p.m.
Detroit at Minnesota, 1 p.m.
Denver at Pittsburgh, 1 p.m.
Miami at Tampa Bay, 1 p.m.
New Orleans at Washington, 1 p.m.
Chicago at Las Vegas, 4:05 p.m.
Cleveland at Los Angeles Chargers, 4:05 p.m.
San Francisco at Arizona, 4:25 p.m.
New York Giants at Dallas, 4:25 p.m.
Buffalo at Kansas City, 8:20 p.m. (SNF)
Monday, Oct. 11
Indianapolis at Baltimore, 8:15 p.m.