The scene shifts to Indianapolis as the Colts host the Tennessee Titans for first place in the AFC South. These two teams played just two weeks ago on a Thursday night as Indy doubled up the Titans 34-17 on the road. Philip Rivers went 29-for-39 for 308 yards with a touchdown in the victory. Ryan Tannehill had one of his worst games of the season, going 15-of-27 for only 147 yards. Indy's defense came up with the stops they needed on the short week.
The Titans (7-3) do have some momentum entering this one after going into Baltimore and leaving with a 30-24 overtime victory. Derrick Henry racked up 133 yards on the ground and scored the game-winning touchdown in OT. It was Corey Davis who was on the receiving end of almost half of Tannehill's passing yards. Even more impressive was the fact that the defense held the Ravens in check when it needed to.
The Colts (7-3) also are feeling good after an overtime victory over the Packers at home. For the second straight week, they put up 34 points, as Rivers threw for nearly 300 yards in the win. Michael Pittman Jr. continues to be one of his favorite targets, leading the team with 66 yards receiving vs. Green Bay. Indy has now won two straight and four of its last five.
Tennessee at Indianapolis
Kickoff: Sunday, Nov. 29 at 1 p.m. ET
Spread: Colts -3
Three Things to Watch
Situationally, this is the Titans' second straight road game and is part of a closing stretch in which they are on the road for five of their final seven overall. Up next for Tennessee is a home game with the Browns, but with revenge in play here, I fully expect a focused effort. The Colts are home for the second straight week. They need to take care of business because three of their next four are away from home, including two contests with the Texans in that stretch.
2. Quick adjustments
When you dig deeper into the box score from the last meeting just two weeks ago, of course, Tennessee will need better production from Ryan Tannehill. It seemed like the Colts were okay with Derrick Henry getting his yards, but they took away the aerial attack. A.J. Brown was really quiet with one reception for 21 yards on just four targets. That has to change, as Tennessee isn't good enough to weather a disappearing act from its No. 1 receiver. On the Indy side, the Colts got a pretty balanced effort last time against the Titans, so they may not need to change much. Rookie Jonathan Taylor was a disappointment with just 12 yards on seven carries, but Nyheim Hines stepped up big in the win.
3. Establish the run
The Colts' backfield has been fascinating to watch this season. Entering the year it was supposed to be a share between Marlon Mack and the rookie Taylor, but Mack got hurt early and Taylor failed to capitalize. From Week 2 until the bye week, the former Badger had just one effort over 70 yards, and that was week two against the Vikings. After the bye, Indy decided to get Jordan Wilkins and Nyheim Hines more work, and both of those guys led the way for the next three weeks. The Titans don't have that problem, although it was interesting that in weeks eight through 10, Henry's snap count was in the 50 percent range. That changed last week when he was in for 79 percent of the snaps. Whoever can establish the run will most likely get the win.
The road team has won four straight and five of the last six in this series. It's so hard to figure out the Titans, but I think they get the win here. Tannehill will play better than he did in the earlier meeting, and it's possible that the Colts' defense got exposed a little bit last week by the Packers. Give me Tennessee on the road here as Henry rumbles for two touchdowns.
Prediction: Titans 24, Colts 20
— Written by Matt Josephs, who is a part of the Athlon Sports Contributor Network. Follow him on Twitter @MidMajorMatt.