Heading into Week 4, fantasy owners should be pretty confident with who will be in their starting lineup. However, there are a number of tight ends that are going to be game-time decisions, which is tough for fantasy owners. Two teams are on a bye, which does limit the pool to pick from if fantasy owners need to scramble to the waiver wire.
A few key players have already been ruled out, including Sammy Watkins (put on IR), Jonathan Stewart, Eric Decker, Donte Moncrief, Eli Rogers and Charcandrick West. There also are some that are listed as Doubtful, meaning they have a 25 percent chance of playing, but most likely won’t see any game action Sunday. That group includes: Jeremy Langford, Jay Cutler, Antonio Gates, Kenneth Dixon and Ka'Deem Carey.
As for those who are Questionable, some are likely going to play, but many are going to require fantasy owners to watch the inactive listings prior to game time. Below you will find the key quarterbacks and tight ends. Don’t forget about the running backs and wide receivers before setting your lineup.
Teams on bye: Green Bay, Philadelphia
Note: All times ET
Jacoby Brissett (thumb) and Jimmy Garoppolo (shoulder), QBs, New England Patriots vs. Buffalo Bills, (1 p.m.)
Both quarterbacks are banged up, and both are questionable. Between the two of them, the Patriots are determined to get through the week until Tom Brady is back. Odds are both will be active and whichever one is healthier will be the one that starts and plays until he can't anymore. Garoppolo is likely the Patriots’ choice to play, but it will depend on how he is progressing from the shoulder injury. If Garoppolo does play, it's a boost for the pass catchers. However, fantasy owners needing to pick a Patriots quarterback will have to wait until Sunday morning to see which QB will get the start.
Rob Gronkowski (hamstring), TE, New England Patriots vs. Buffalo Bills, (1 p.m.)
Gronkowski put in limited practices all week as he has done all season. Fantasy owners that were anxious to get their No. 1 draft pick into lineups started him in Week 3, only to be rewarded with a goose egg. It's hard to trust Gronk and it's hard to sit Gronk. The good news is he made it through Week 3 without suffering a setback and has had additional time to rest (the Patriots last played Sept. 22). He's a TE1 when active, but fantasy owners need to temper expectations.
Delanie Walker (hamstring), TE, Tennessee Titans at Houston Texans, (1 p.m.)
Walker missed Week 3 because of the hamstring injury, and he's going to be a game-time decision for Week 4. Luckily for fantasy owners, the Titans play at 1 p.m. on Sunday, so they will know early if they need a replacement again. He's put in limited practices this week, but the team will likely see how he feels in warm ups. He's a TE2 if active, but be sure to watch the inactive report before kickoff.
Jimmy Graham (knee, back), TE, Seattle Seahawks at New York Jets, (1 p.m.)
Graham gave fantasy owners a scare when he sat out practice on Thursday, but after practicing fully on Friday, he is on track to play on Sunday. In Week 3, he had six receptions for 100 yards and a touchdown and looked like the old Graham again. The Seahawks are looking to get him more involved, especially in the red zone, so he is a low TE1 for Week 4. The Jets did allow Kelce to have a nice game (6-89-1) in Week 3, so the defense is beatable.
Julius Thomas (elbow), TE, Jacksonville Jaguars vs. Indianapolis Colts (9:30 a.m., London)
Thomas played through Week 3 and didn't appear to be injured, although he did only have two receptions for 13 yards. He showed up on the practice report with the elbow injury on Wednesday and missed practice on Thursday as well. He put in a limited session on Friday, which may mean he is ready to play. Because the inactive list for this game will be announced extra early, fantasy owners should just stay tuned as he is going to be a game-time decision. If active, he's a TE1.
Eric Ebron (ankle), TE, Detroit Lions at Chicago Bears, (1 p.m.)
Despite the questionable tag, all signs point to Ebron playing. He's been dealing with an ankle injury and he appeared to tweak it in Week 3. However, after sitting out Wednesday's practice, he had a limited session Thursday and a full practice on Friday. He's on track to play against Chicago and is on the TE1 radar.
Vance McDonald (hip), TE, San Francisco 49ers vs. Dallas Cowboys (4:25 p.m.)
While most fantasy owners aren't starting McDonald, he may be someone that Delanie Walker owners may be considering. He left Week 3 with a hip injury and after missing Wednesday's practice, returned in a limited fashion. He's not someone worth picking up as he's heading to be a game-time decision. Between the injury and playing in the later round of games on Sunday, leave McDonald out of fantasy lineups.
— Written by Sarah Lewis, who is part of the Athlon Contributor network and lives, eats, and breathes fantasy football. She also writes for SoCalledFantasyExperts.com among other sites. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.