There are just a few late games in Week 6 because of four teams being on bye, but there are still plenty of key fantasy running backs on the injury report. Don’t forget to read up on those in the early games to get the complete RB picture, as well as the injury story for QBs, WRs (early games, later games) and TEs.
Teams on bye: Dallas, Oakland, St. Louis, Tampa Bay
Marshawn Lynch, RB, Seattle Seahawks vs. Carolina Panthers, Sunday, 4:05 p.m. ET
Questionable – Hamstring
After missing two games with back/calf/hamstring injuries, Lynch appears to be good to go for Sunday. He has been able to practice in full this week and even though the Seahawks play later on Sunday, fantasy owners can pencil Lynch into their lineups. The Panthers are coming off a bye, but are making the cross-country trip to Seattle to play, which is never easy. Lynch is a RB1.
Justin Forsett, RB, Baltimore Ravens at San Francisco 49ers, Sunday 4:25 p.m. ET
Questionable – Ankle
The good news for Forsett owners is that he returned to practice on Friday after missing Wednesday and Thursday. He injured the ankle in Week 5 and wasn't able to play in the overtime period. However, it looks like he will be active on Sunday. He's coming off back-to-back 100-yard games, and is a RB1, despite the ankle injury.
Carlos Hyde, RB, San Francisco 49ers vs. Baltimore Ravens, Sunday 4:25 p.m. ET
Questionable – Foot
Even though Hyde was given a questionable tag, all signs point to him playing on Sunday. The 49ers are limiting his practice reps because he's basically their only running back. He's a solid RB2 for Week 6 as he has been inconsistent this season.
Dion Lewis, RB, New England Patriots at Indianapolis Colts, Sunday, 8:30 p.m. ET
Questionable – Abdomen
Even though Lewis put in limited practices, the word out of New England is that he will be active on Sunday night. It's tough on fantasy owners because of the late start time, but it does appear he will be active. He's a RB1 if active. If for some reason he does sit, LeGarrette Blount will move into RB1 territory.
Ryan Mathews, RB, Philadelphia Eagles vs. New York Giants, Monday, 8:30 p.m. ET
Questionable – Groin
Savvy fantasy owners may have noticed that Mathews showed up on the injury report on Friday with a groin injury. He was given a questionable tag, but he is expected to play. He's scored touchdowns in three of the five games so far, and even with DeMarco Murray active, he's a RB2, assuming he plays. If he does not play, be sure you have Darren Sproles as a fill-in.
Reggie Bush, RB, San Francisco 49ers vs. Baltimore Ravens, Sunday 4:25 p.m. ET
Doubtful – Calf
Bush had a setback with the calf injury that has already forced him to miss most of the season. He can't stay healthy, which just means more carries for Carlos Hyde.
— Written by Sarah Lewis, who is part of the Athlon Contributor network and lives, eats, and breathes fantasy football. She also writes for SoCalledFantasyExperts.com among other sites. Have a fantasy football question? Send it to her on Twitter @Sarah_Lewis32.