Jacobs injured his MCL last week. The extent of his injury is unknown, but there should be more information available early next week to see if he only needs one week off, or if he'll be shelved for longer.
As always, bad news for one fantasy owner is good news for another. Ahmad Bradshaw owners should see an increase in production, as Bradshaw will carry the bulk of the load (as well as goal line chances) and get somewhere between 20-30 touches today against a pretty good Seahawks run defense.
Danny Ware will slide in as Bradshaw's primary bakc-up. He's worth keeping an eye on if Jacobs is out for an extended period of time. Or if Bradshaw gets dinged up today. Ware doesn't have much experience, but you never know where you can squeeze some unexpected production from in a fantasy season, especially as bye weeks start to rear their ugly heads.